(data stored in SCRATCH3701 zone)

HOGENOM6: MYCA9_2_PE19

ID   MYCA9_2_PE19                         STANDARD;      PRT;   839 AA.
AC   MYCA9_2_PE19; B1ME58;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase (MYCA9_2.PE19) (Subunit A) GyrA (DNA
DE   topoisomerase); .
GN   OrderedLocusNames=MAB_0019;
OS   MYCOBACTERIUM ABSCESSUS ATCC 19977.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
OC   abscessus.
OX   NCBI_TaxID=561007;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MYCA9_2.PE19.
CC       Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:B1ME58_MYCA9
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B1ME58; -.
DR   EMBL; CU458896; CAM60122.1; -; Genomic_DNA.
DR   RefSeq; YP_001700776.1; NC_010397.1.
DR   ProteinModelPortal; B1ME58; -.
DR   STRING; B1ME58; -.
DR   EnsemblBacteria; EBMYCT00000008085; EBMYCP00000008024; EBMYCG00000008083.
DR   GeneID; 5962565; -.
DR   GenomeReviews; CU458896_GR; MAB_0019.
DR   KEGG; mab:MAB_0019; -.
DR   GeneTree; EBGT00050000016653; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; MYCA9_2.PE19; -.
DR   PRODOM; MYCA9_2_PE19.
DR   SWISS-2DPAGE; MYCA9_2_PE19.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   839 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDTTLPPGG DDAVDRIEPV DIQQEMQRSY IDYAMSVIVG RALPEVRDGL KPVHRRVLYA
     MYDSGFRPDR SHAKSARSVA ETMGNYHPHG DASIYDTLVR MAQPWSLRYP LVDGQGNFGS
     PGNDPAAAMR YTEARLTPLA MEMLREIDEE TVDFIPNYDG RVMEPTVLPS RFPNLLANGS
     GGIAVGMATN MPPHNLRELA EAVYWALDNH EADEETTLKA VCEKITGPDF PTSGLIVGTQ
     GIHDAYTTGR GSIRMRGVAE IEEDSKGRTS LVITELPYQV NHDNFITSIA EQVRDGKIAG
     ISNIEDQSSD RVGLRIVVVL KRDAVAKVVL NNLYKHTQLQ TSFGANMLSI VDGVPRTLRL
     DQLIRLYVNH QLDVIIRRTR YRLRKANERA HILRGLVKAL DALDEVIALI RASQTVDIAR
     TGLIELLDVD EIQAQAILDM QLRRLAALER QKIIDDLAKI EAEIADLEDI LAKPERQRAI
     VKDELAEITE KYGDDRRTRI ISADGDVADE DLIAREDVVV TITETGYAKR TKTDLYRSQK
     RGGKGVQGAG LKQDDIVKHF FVCSTHDWIL FFTTKGRVYR AKAYDLPEAA RTARGQHVAN
     LLAFQPEERI AQVIQIKSYE DAPYLVLATK NGLVKKSKLT EFDSNRSGGL VAVNLRDGDE
     LVGAVLCSAE DDLLLVSAHG QSIRFSATDE ALRPMGRATS GVQGMRFNGE DDLLSLNVVR
     EGTYLLVATS GGYSKRTAIE EYPVQGRGGK GVLTVQYDPR RGSLVGALVV DEESELYAIT
     SGGGVIRTIA KQVRKAGRQT KGVRLMNLGE GDTLLAIAHN ADEGDADPDE DAAGTTAGE
//

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