(data stored in ACNUC7421 zone)

HOGENOM: MYCTK_1_PE1

ID   MYCTK_1_PE1                          STANDARD;      PRT;   507 AA.
AC   MYCTK_1_PE1; C6DQ76;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (MYCTK_1.PE1).
GN   Name=dnaA; OrderedLocusNames=TBMG_00001;
OS   MYCOBACTERIUM TUBERCULOSIS KZN 1435.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
OC   tuberculosis complex.
OX   NCBI_TaxID=478434;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MYCTK_1.PE1.
CC       Mycobacterium tuberculosis KZN 1435, complete genome.
CC       chromosome, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:C6DQ76_MYCTK
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C6DQ76; -.
DR   EMBL; CP001658; ACT23022.1; -; Genomic_DNA.
DR   RefSeq; YP_003029917.1; NC_012943.1.
DR   ProteinModelPortal; C6DQ76; -.
DR   STRING; C6DQ76; -.
DR   EnsemblBacteria; EBMYCT00000094138; EBMYCP00000087751; EBMYCG00000091855.
DR   GeneID; 8161237; -.
DR   GenomeReviews; CP001658_GR; TBMG_00001.
DR   KEGG; mtb:TBMG_00001; -.
DR   GeneTree; EBGT00050000017320; -.
DR   ProtClustDB; PRK00149; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; MYCTK_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   507 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDDPGSGFT TVWNAVVSEL NGDPKVDDGP SSDANLSAPL TPQQRAWLNL VQPLTIVEGF
     ALLSVPSSFV QNEIERHLRA PITDALSRRL GHQIQLGVRI APPATDEADD TTVPPSENPA
     TTSPDTTTDN DEIDDSAAAR GDNQHSWPSY FTERPHNTDS ATAGVTSLNR RYTFDTFVIG
     ASNRFAHAAA LAIAEAPARA YNPLFIWGES GLGKTHLLHA AGNYAQRLFP GMRVKYVSTE
     EFTNDFINSL RDDRKVAFKR SYRDVDVLLV DDIQFIEGKE GIQEEFFHTF NTLHNANKQI
     VISSDRPPKQ LATLEDRLRT RFEWGLITDV QPPELETRIA ILRKKAQMER LAVPDDVLEL
     IASSIERNIR ELEGALIRVT AFASLNKTPI DKALAEIVLR DLIADANTMQ ISAATIMAAT
     AEYFDTTVEE LRGPGKTRAL AQSRQIAMYL CRELTDLSLP KIGQAFGRDH TTVMYAQRKI
     LSEMAERREV FDHVKELTTR IRQRSKR
//

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