(data stored in SCRATCH3701 zone)

HOGENOM6: MYCUA_2_PE6

ID   MYCUA_2_PE6                          STANDARD;      PRT;   839 AA.
AC   MYCUA_2_PE6; A0PKB7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase (MYCUA_2.PE6) (Subunit A) GyrA; .
GN   Name=gyrA; OrderedLocusNames=MUL_0006;
OS   MYCOBACTERIUM ULCERANS AGY99.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium.
OX   NCBI_TaxID=362242;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MYCUA_2.PE6.
CC       Mycobacterium ulcerans Agy99, complete genome.
CC       chromosome, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:A0PKB7_MYCUA
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A0PKB7; -.
DR   EMBL; CP000325; ABL02786.1; -; Genomic_DNA.
DR   RefSeq; YP_904257.1; NC_008611.1.
DR   ProteinModelPortal; A0PKB7; -.
DR   STRING; A0PKB7; -.
DR   EnsemblBacteria; EBMYCT00000075649; EBMYCP00000073654; EBMYCG00000075644.
DR   GeneID; 4553250; -.
DR   GenomeReviews; CP000325_GR; MUL_0006.
DR   KEGG; mul:MUL_0006; -.
DR   GenoList; MUL_0006; -.
DR   eggNOG; COG0188; -.
DR   GeneTree; EBGT00050000016653; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:2.120.10.30; 6-blade_b-propeller_TolB-like; 1.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; MYCUA_2.PE6; -.
DR   PRODOM; MYCUA_2_PE6.
DR   SWISS-2DPAGE; MYCUA_2_PE6.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   839 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDTMLPPGG EASDRIEPVD IQQEMQRSYI DYAMSVIVGR ALPEVRDGLK PVHRRVLYAM
     YDSGFRPDHS HAKSARSVAE TMGNYHPHGD ASIYDTLVRM AQPWSLRYPL VDGQGNFGSP
     GNDPPAAMRY TEARLTPLAM EMLREIDEET VDFIPNYDGR VQEPTVLPSR FPNLLANGSG
     GIAVGMATNI PPHNLRELAE AVFWCLENHD ADEEATLAAV TDRVKGPDFP TSGLIVGTQG
     ISDAYKTGRG SIRMRGVVEI EEDSRGRTSL VITELPYQVN HDNFITSIAE QVRDGKLAGI
     SNIEDQSSDR VGLRIVVEIK RDAVAKVVLN NLYKHTQLQT SFGANMLSIV DGVPRTLRLD
     QMIRYYVEHQ LDVTIRRTTY RLRKANERAH ILRGLVKALD ALDEVIALIR ASQTVDIARA
     GLIELLGIDE IQAQAILDMQ LRRLAALERE RIVDDLAKIE AEIADLEDIL AKPERQRAIV
     RDELAEIVDK HGDDRRTRII AADGDVSDED LIAREDVVVT ITETGYAKRT KTDLYRSQKR
     GGKGVQGAGL KQDDIVRHFF VCSTHDWILF FTTQGRVYRA KAYELPEALR TARGQHVANL
     LAFQPEERIA QVIQIKSYED APYLVLATQN GVVKKSKLTD FDSNRSGGIV AINLRGEDEL
     VGAVLCSSEE DLLLVSANGQ SIRFSATDEA LRPMGRATSG VQGMRFNADD RLLSLNVVRE
     GTYLLAATAG GYAKRTGIEE YPVQGRGGKG VLTIMYDRRR GRLVGALIVD DDSELYAITS
     GGGVIRTAAR QVRKAGRQTK GVRLMNLGEG DTLLAIARNA EENADEAVAE ATDTDESSN
//

If you have problems or comments...

PBIL Back to PBIL home page