(data stored in ACNUC30630 zone)

HOGENOM: MYLEP1_1_PE1192

ID   MYLEP1_1_PE1192                      STANDARD;      PRT;   320 AA.
AC   MYLEP1_1_PE1192; Q9X796;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=tRNA pseudouridine synthase A; EC=5.4.99 12;AltName:
DE   Full=tRNA pseudouridine(38-40) synthase;AltName: Full=tRNA
DE   pseudouridylate synthase I;AltName: Full=tRNA-uridine isomerase I;
DE   (MYLEP1_1.PE1192).
GN   Name=truA; OrderedLocusNames=ML1955; ORFNames=MLCB1222.25c;
OS   MYCOBACTERIUM LEPRAE TN.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MYLEP1_1.PE1192.
CC       Mycobacterium leprae TN chromosome, complete genome.
CC       chromosome, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:TRUA_MYCLE
CC   -!- FUNCTION: Formation of pseudouridine at positions 38, 39 and 40 in
CC       the anticodon stem and loop of transfer RNAs (By similarity).
CC   -!- CATALYTIC ACTIVITY: tRNA uridine(38-40) = tRNA pseudouridine(38-
CC       40).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA
CC       family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB39831.1; Type=Erroneous initiation;
CC       Sequence=CAC30910.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000248674 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q9X796; -.
DR   EMBL; AL049491; CAB39831.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL583923; CAC30910.1; ALT_INIT; Genomic_DNA.
DR   PIR; F87153; F87153.
DR   RefSeq; NP_302320.2; NC_002677.1.
DR   ProteinModelPortal; Q9X796; -.
DR   EnsemblBacteria; EBMYCT00000029226; EBMYCP00000028832; EBMYCG00000029221.
DR   GeneID; 909431; -.
DR   GenomeReviews; AL450380_GR; ML1955.
DR   KEGG; mle:ML1955; -.
DR   Leproma; ML1955; -.
DR   GeneTree; EBGT00050000017011; -.
DR   ProtClustDB; PRK00021; -.
DR   BioCyc; MLEP272631:ML1955-MON; -.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:EC.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   HAMAP; MF_00171; TruA; 1; -.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR   InterPro; IPR001406; PsdUridine_synth_TruA.
DR   InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR   InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR   InterPro; IPR020094; PsdUridine_synth_TruA_N.
DR   Gene3D; G3DSA:3.30.70.580; PseudoU_synth_1; 1.
DR   Gene3D; G3DSA:3.30.70.660; PseudoU_synth_1; 1.
DR   PANTHER; PTHR11142; PseudoU_synth_1; 1.
DR   Pfam; PF01416; PseudoU_synth_1; 2.
DR   PIRSF; PIRSF001430; tRNA_psdUrid_synth; 1.
DR   SUPFAM; SSF55120; PsdUridine_synth_cat_dom; 1.
DR   TIGRFAMs; TIGR00071; HisT_truA; 1.
DR   HOGENOMDNA; MYLEP1_1.PE1192; -.
KW   Complete proteome; Isomerase; tRNA processing.
SQ   SEQUENCE   320 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPPLRPKQRR PKRSRLKRRR SKPRRTRWPT PASLTRPPNI SEDVRLRLDI AYDGTDFAGW
     AVQAGQRTVA GVLDEAFTTV FRTPVRLRAA GRTDTGVHAT GQVAHVDIPG TALSKANPRS
     PHTGDPEFLP LLRRLSRLLP VDVRVLDIAC APVGFDARFS ALRRHYRYRL STAPYGVQPN
     QARYVTAWPR ELDLDSMSAA SRDLLGLRDF AVFCRHRHGA TTIRELQRLE WSREGYLITA
     HITADAFCWS MVRSLIGALL AVGDHRRTIG WCGELLTKAS RSSDFTTAPA HGLTFIRVDY
     PPDDELAERA VITRDLRSSF
//

If you have problems or comments...

PBIL Back to PBIL home page