(data stored in ACNUC7421 zone)

HOGENOM: MYTUB1_1_PE1274

ID   MYTUB1_1_PE1274                      STANDARD;      PRT;   563 AA.
AC   MYTUB1_1_PE1274; Q11039;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Cold-shock DEAD box protein A homolog; EC=3.6.4 13;AltName:
DE   Full=ATP-dependent RNA helicase deaD homolog; (MYTUB1_1.PE1274).
GN   Name=deaD; Synonyms=csdA; OrderedLocusNames=Rv1253, MT1292;
OS   MYCOBACTERIUM TUBERCULOSIS H37RV.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
OC   tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MYTUB1_1.PE1274.
CC       Mycobacterium tuberculosis H37Rv, complete genome.
CC       1..69269 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:DEAD_MYCTU
CC   -!- FUNCTION: Has a helix-destabilizing activity (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC   -!- SIMILARITY: Contains 1 helicase ATP-binding domain.
CC   -!- SIMILARITY: Contains 1 helicase C-terminal domain.
CC   -!- GENE_FAMILY: HOG000268810 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q11039; -.
DR   EMBL; BX842576; CAB00899.1; -; Genomic_DNA.
DR   EMBL; AE000516; AAK45550.1; -; Genomic_DNA.
DR   PIR; E70752; E70752.
DR   RefSeq; NP_215769.1; NC_000962.2.
DR   RefSeq; NP_335736.1; NC_002755.2.
DR   ProteinModelPortal; Q11039; -.
DR   EnsemblBacteria; EBMYCT00000002426; EBMYCP00000002426; EBMYCG00000002424.
DR   EnsemblBacteria; EBMYCT00000070115; EBMYCP00000068174; EBMYCG00000070110.
DR   GeneID; 887069; -.
DR   GeneID; 924778; -.
DR   GenomeReviews; AE000516_GR; MT1292.
DR   GenomeReviews; AL123456_GR; Rv1253.
DR   KEGG; mtc:MT1292; -.
DR   KEGG; mtu:Rv1253; -.
DR   TIGR; MT1292; -.
DR   TubercuList; Rv1253; -.
DR   GeneTree; EBGT00050000015683; -.
DR   OMA; FLEVEDF; -.
DR   ProtClustDB; CLSK791051; -.
DR   GO; GO:0005829; C:cytosol; IDA:MTBBASE.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   InterPro; IPR005580; DbpA_RNA-bd.
DR   InterPro; IPR014001; DEAD-like_helicase.
DR   InterPro; IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF03880; DbpA; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
DR   HOGENOMDNA; MYTUB1_1.PE1274; -.
KW   cold-shock DEAD-box protein A;
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome; RNA-binding; Transcription;
KW   Transcription regulation.
SQ   SEQUENCE   563 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAFPEYSPAA SAATFADLQI HPRVLRAIGD VGYESPTAIQ AATIPALMAG SDVVGLAQTG
     TGKTAAFAIP MLSKIDITSK VPQALVLVPT RELALQVAEA FGRYGAYLSQ LNVLPIYGGS
     SYAVQLAGLR RGAQVVVGTP GRMIDHLERA TLDLSRVDFL VLDEADEMLT MGFADDVERI
     LSETPEYKQV ALFSATMPPA IRKLSAKYLH DPFEVTCKAK TAVAENISQS YIQVARKMDA
     LTRVLEVEPF EAMIVFVRTK QATEEIAEKL RARGFSAAAI SGDVPQAQRE RTITALRDGD
     IDILVATDVA ARGLDVERIS HVLNYDIPHD TESYVHRIGR TGRAGRSGAA LIFVSPRELH
     LLKAIEKATR QTLTEAQLPT VEDVNTQRVA KFADSITNAL GGPGIELFRR LVEEYEREHD
     VPMADIAAAL AVQCRGGEAF LMAPDPPLSR RNRDQRRDRP QRPKRRPDLT TYRVAVGKRH
     KIGPGAIVGA IANEGGLHRS DFGQIRIGPD FSLVELPAKL PRATLKKLAQ TRISGVLIDL
     RPYRPPDAAR RHNGGKPRRK HVG
//

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