(data stored in ACNUC1104 zone)

HOGENOM: MYTUB1_1_PE2891

ID   MYTUB1_1_PE2891                      STANDARD;      PRT;   530 AA.
AC   MYTUB1_1_PE2891; O05813; Q50747; Q7D6G8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Uncharacterized MFS-type transporter efpA;AltName:
DE   Full=Efflux protein A; (MYTUB1_1.PE2891).
GN   Name=efpA; OrderedLocusNames=Rv2846c, MT2912;
OS   MYCOBACTERIUM TUBERCULOSIS H37RV.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
OC   tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MYTUB1_1.PE2891.
CC       Mycobacterium tuberculosis H37Rv, complete genome.
CC       1..69269 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:EFPA_MYCTU
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Potential).
CC   -!- INDUCTION: Expressed during infection of macrophages.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC   -!- GENE_FAMILY: HOG000239124 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; O05813; Q50747; Q7D6G8; -.
DR   EMBL; L39922; AAA85344.1; -; Genomic_DNA.
DR   EMBL; BX842581; CAB08444.1; -; Genomic_DNA.
DR   EMBL; AE000516; AAK47238.1; -; Genomic_DNA.
DR   PIR; A70589; A70589.
DR   RefSeq; NP_217362.1; NC_000962.2.
DR   RefSeq; NP_337424.1; NC_002755.2.
DR   ProteinModelPortal; O05813; -.
DR   EnsemblBacteria; EBMYCT00000001073; EBMYCP00000001073; EBMYCG00000001073.
DR   EnsemblBacteria; EBMYCT00000071483; EBMYCP00000069542; EBMYCG00000071478.
DR   GeneID; 888575; -.
DR   GeneID; 925363; -.
DR   GenomeReviews; AE000516_GR; MT2912.
DR   GenomeReviews; AL123456_GR; Rv2846c.
DR   KEGG; mtc:MT2912; -.
DR   KEGG; mtu:Rv2846c; -.
DR   TIGR; MT2912; -.
DR   TubercuList; Rv2846c; -.
DR   GeneTree; EBGT00050000014781; -.
DR   OMA; TRETETA; -.
DR   ProtClustDB; CLSK792121; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0040007; P:growth; IMP:MTBBASE.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR016196; MFS_dom_general_subst_transpt.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   HOGENOMDNA; MYTUB1_1.PE2891; -.
KW   integral membrane efflux protein EfpA;
KW   Cell membrane; Complete proteome; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   530 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTALNDTERA VRNWTAGRPH RPAPMRPPRS EETASERPSR YYPTWLPSRS FIAAVIAIGG
     MQLLATMDST VAIVALPKIQ NELSLSDAGR SWVITAYVLT FGGLMLLGGR LGDTIGRKRT
     FIVGVALFTI SSVLCAVAWD EATLVIARLS QGVGSAIASP TGLALVATTF PKGPARNAAT
     AVFAAMTAIG SVMGLVVGGA LTEVSWRWAF LVNVPIGLVM IYLARTALRE TNKERMKLDA
     TGAILATLAC TAAVFAFSIG PEKGWMSGIT IGSGLVALAA AVAFVIVERT AENPVVPFHL
     FRDRNRLVTF SAILLAGGVM FSLTVCIGLY VQDILGYSAL RAGVGFIPFV IAMGIGLGVS
     SQLVSRFSPR VLTIGGGYLL FGAMLYGSFF MHRGVPYFPN LVMPIVVGGI GIGMAVVPLT
     LSAIAGVGFD QIGPVSAIAL MLQSLGGPLV LAVIQAVITS RTLYLGGTTG PVKFMNDVQL
     AALDHAYTYG LLWVAGAAII VGGMALFIGY TPQQVAHAQE VKEAIDAGEL
//

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