(data stored in ACNUC30630 zone)

HOGENOM: MYTUB1_1_PE3513

ID   MYTUB1_1_PE3513                      STANDARD;      PRT;   297 AA.
AC   MYTUB1_1_PE3513; P65846; O06322;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=tRNA pseudouridine synthase A; EC=5.4.99 12;AltName:
DE   Full=tRNA pseudouridine(38-40) synthase;AltName: Full=tRNA
DE   pseudouridylate synthase I;AltName: Full=tRNA-uridine isomerase I;
DE   (MYTUB1_1.PE3513).
GN   Name=truA; OrderedLocusNames=Rv3455c, MT3562; ORFNames=MTCY13E12.08c;
OS   MYCOBACTERIUM TUBERCULOSIS H37RV.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium
OC   tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MYTUB1_1.PE3513.
CC       Mycobacterium tuberculosis H37Rv, complete genome.
CC       1..69269 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:TRUA_MYCTU
CC   -!- FUNCTION: Formation of pseudouridine at positions 38, 39 and 40 in
CC       the anticodon stem and loop of transfer RNAs (By similarity).
CC   -!- CATALYTIC ACTIVITY: tRNA uridine(38-40) = tRNA pseudouridine(38-
CC       40).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA
CC       family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB08721.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000248674 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P65846; O06322; -.
DR   EMBL; BX842583; CAB08721.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE000516; AAK47901.1; -; Genomic_DNA.
DR   PIR; D70565; D70565.
DR   RefSeq; NP_217972.2; NC_000962.2.
DR   RefSeq; NP_338087.1; NC_002755.2.
DR   ProteinModelPortal; P65846; -.
DR   EnsemblBacteria; EBMYCT00000002601; EBMYCP00000002601; EBMYCG00000002599.
DR   EnsemblBacteria; EBMYCT00000071399; EBMYCP00000069458; EBMYCG00000071394.
DR   GeneID; 887590; -.
DR   GeneID; 922954; -.
DR   GenomeReviews; AE000516_GR; MT3562.
DR   GenomeReviews; AL123456_GR; Rv3455c.
DR   KEGG; mtc:MT3562; -.
DR   KEGG; mtu:Rv3455c; -.
DR   TIGR; MT3562; -.
DR   TubercuList; Rv3455c; -.
DR   GeneTree; EBGT00050000017011; -.
DR   OMA; QANAFVH; -.
DR   ProtClustDB; PRK00021; -.
DR   GO; GO:0005618; C:cell wall; IDA:MTBBASE.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:EC.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0040007; P:growth; IMP:MTBBASE.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   HAMAP; MF_00171; TruA; 1; -.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR   InterPro; IPR001406; PsdUridine_synth_TruA.
DR   InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR   InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR   InterPro; IPR020094; PsdUridine_synth_TruA_N.
DR   Gene3D; G3DSA:3.30.70.580; PseudoU_synth_1; 1.
DR   Gene3D; G3DSA:3.30.70.660; PseudoU_synth_1; 1.
DR   PANTHER; PTHR11142; PseudoU_synth_1; 1.
DR   Pfam; PF01416; PseudoU_synth_1; 2.
DR   PIRSF; PIRSF001430; tRNA_psdUrid_synth; 1.
DR   SUPFAM; SSF55120; PsdUridine_synth_cat_dom; 1.
DR   TIGRFAMs; TIGR00071; HisT_truA; 1.
DR   HOGENOMDNA; MYTUB1_1.PE3513; -.
KW   Complete proteome; Isomerase; Reference proteome; tRNA processing.
SQ   SEQUENCE   297 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLTRRPPKS PPQRPPRISG VVRLRLDIAY DGTDFAGWAA QVGQRTVAGD LDAALTTIFR
     TPVRLRAAGR TDAGVHASGQ VAHVDVPADA LPNAYPRAGH VGDPEFLPLL RRLGRFLPAD
     VRILDITRAP AGFDARFSAL RRHYVYRLST APYGVEPQQA RYITAWPREL DLDAMTAASR
     DLMGLHDFAA FCRHREGATT IRDLQRLDWS RAGTLVTAHV TADAFCWSMV RSLVGALLAV
     GEHRRATTWC RELLTATGRS SDFAVAPAHG LTLIQVDYPP DDQLASRNLV TRDVRSG
//

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