(data stored in ACNUC7421 zone)

HOGENOM: NEIG1_1_PE1

ID   NEIG1_1_PE1                          STANDARD;      PRT;   518 AA.
AC   NEIG1_1_PE1; Q5FAJ2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (NEIG1_1.PE1).
GN   Name=dnaA; OrderedLocusNames=NGO0001;
OS   NEISSERIA GONORRHOEAE FA 1090.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=242231;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEIG1_1.PE1.
CC       Neisseria gonorrhoeae FA 1090, complete genome.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:DNAA_NEIG1
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- GENE_FAMILY: HOG000235659 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5FAJ2; -.
DR   EMBL; AE004969; AAW88774.1; -; Genomic_DNA.
DR   RefSeq; YP_207186.1; NC_002946.2.
DR   ProteinModelPortal; Q5FAJ2; -.
DR   STRING; Q5FAJ2; -.
DR   EnsemblBacteria; EBNEIT00000002161; EBNEIP00000002002; EBNEIG00000002161.
DR   GeneID; 3283049; -.
DR   GenomeReviews; AE004969_GR; NGO0001.
DR   KEGG; ngo:NGO0001; -.
DR   NMPDR; fig|242231.4.peg.529; -.
DR   eggNOG; COG0593; -.
DR   GeneTree; EBGT00050000020884; -.
DR   OMA; WPLCLRR; -.
DR   PhylomeDB; Q5FAJ2; -.
DR   ProtClustDB; PRK00149; -.
DR   BioCyc; NGON242231:NGO0001-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; NEIG1_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
SQ   SEQUENCE   518 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTLAEFWPLC LRRLHDMLPH GQFAQWIAPL TVGEEGGVWV VYGKNQFACN MLKSQFAGKI
     EAVREELAAG RPAFVFKPGE GVRYEMAAVE GAVEPAEPSL HAGSEEMPVQ EVLLDELPSE
     KPVKPAASKT AADILAERMK NLPHEPRQAA GPASRPESAA VAKARTDAQR DAEEARYEQT
     NLSPDYTFDT LVEGKGNRLA AAAAQAIAEN PGQSYNPFFL YGSTGLGKTH LVQAVGNELL
     KNRPDAKVRY MHSDDYIRSF MKAVRNNTYD VFKQQYKQYD LLIIDDIQFI KGKDRTMEEF
     FYLYNHFHNE KKQLILTCDV LPAKIEGMDD RLKSRFSWGL TLELEPPELE MRIAILQKKA
     EAAGISIEDE AALFIANLIR SNVRELEGAF NRVGASSRFM NRPVIDIDLA RTALQDIIAE
     KHKVITADII IDAVAKYYRI KISDVLGKKR TRNIARPRQV AMSLTKELTT LSLPSIGDSF
     GGRDHTTVMH GIRAVAKLRE EDPELAQDYE KLLILIQN
//

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