(data stored in ACNUC30630 zone)

HOGENOM: NEIG1_1_PE800

ID   NEIG1_1_PE800                        STANDARD;      PRT;   491 AA.
AC   NEIG1_1_PE800; Q5F8B4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Anthranilate synthase component 1; EC=4.1.3 27;AltName:
DE   Full=Anthranilate synthase component I; (NEIG1_1.PE800).
GN   Name=trpE; OrderedLocusNames=NGO0872;
OS   NEISSERIA GONORRHOEAE FA 1090.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=242231;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEIG1_1.PE800.
CC       Neisseria gonorrhoeae FA 1090, complete genome.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:TRPE_NEIG1
CC   -!- CATALYTIC ACTIVITY: Chorismate + L-glutamine = anthranilate +
CC       pyruvate + L-glutamate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 1/5.
CC   -!- SUBUNIT: Tetramer of two components I and two components II (By
CC       similarity).
CC   -!- MISCELLANEOUS: Component I catalyzes the formation of anthranilate
CC       using ammonia rather than glutamine, whereas component II provides
CC       glutamine amidotransferase activity.
CC   -!- SIMILARITY: Belongs to the anthranilate synthase component I
CC       family.
CC   -!- GENE_FAMILY: HOG000025142 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5F8B4; -.
DR   EMBL; AJ242839; CAB45014.1; -; Genomic_DNA.
DR   EMBL; AE004969; AAW89573.1; -; Genomic_DNA.
DR   RefSeq; YP_207985.1; NC_002946.2.
DR   ProteinModelPortal; Q5F8B4; -.
DR   STRING; Q5F8B4; -.
DR   EnsemblBacteria; EBNEIT00000002489; EBNEIP00000002330; EBNEIG00000002489.
DR   GeneID; 3281838; -.
DR   GenomeReviews; AE004969_GR; NGO0872.
DR   KEGG; ngo:NGO0872; -.
DR   NMPDR; fig|242231.4.peg.238; -.
DR   eggNOG; COG0147; -.
DR   GeneTree; EBGT00050000020301; -.
DR   OMA; PSQRMSM; -.
DR   PhylomeDB; Q5F8B4; -.
DR   ProtClustDB; PRK13565; -.
DR   BioCyc; NGON242231:NGO0872-MON; -.
DR   GO; GO:0004049; F:anthranilate synthase activity; IEA:EC.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR019999; Anth_synth_I.
DR   InterPro; IPR006805; Anth_synth_I_N.
DR   InterPro; IPR005256; Anth_synth_I_PabB.
DR   InterPro; IPR015890; Chorismate-bd_C.
DR   Gene3D; G3DSA:3.60.120.10; TRPE_1_chor_bd; 1.
DR   Pfam; PF04715; Anth_synt_I_N; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   PRINTS; PR00095; ANTSNTHASEI.
DR   SUPFAM; SSF56322; TRPE_1_chor_bd; 1.
DR   TIGRFAMs; TIGR00564; TrpE_most; 1.
DR   HOGENOMDNA; NEIG1_1.PE800; -.
KW   anthranilate synthase component I;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Lyase; Reference proteome; Tryptophan biosynthesis.
SQ   SEQUENCE   491 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MISKQEYQAQ AAQGYNRIPL VQELLADLDT PLSLYLKLAN RPYTYLLESV VGGERFGRYS
     FIGLPCSHYL KAGGKHVDVY QNGEIVEQYD GNPLPFIEAF HNRFKTPEIP SLPRFTGGLV
     GYFGYETVYN FEHFAHRLKN TAKANPLGTP DILLMLSQEL AVIDNLSGKI HLIVYADPSQ
     PDSYERARER LEDIRTQLRQ SCAIPLSLGS KQTQAVSEFG EEPFKACVDK IKDYIFAGDC
     MQVVPSQRMS MEFTDNPLAL YRALRTLNPS PYLFYYDFGD FHIVGSSPEI LVRRERDDVI
     VRPIAGTRLR GKTPAEDLAN EQDLLSDAKE IAEHVMLIDL GRNDVGRISK TGEVKVTDKM
     VIEKYSHVMH IVSNVEGCLK EGVTNMDILA ATFPAGTLSG APKVRAMEII EEIEPEKRGI
     YGGAVGVWGF NNDMDLAIAI RTAVIKNNTL FIQSGAGVVA DSDPTSEWQE TQNKARAVVR
     AAQMVQEGLD K
//

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