(data stored in SCRATCH zone)

HOGENOM: NEIL0_1_PE1

ID   NEIL0_1_PE1                          STANDARD;      PRT;   307 AA.
AC   NEIL0_1_PE1; E4Z9Q1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
DE   deacetylase; EC=3.5.1 -;AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase;
DE   (NEIL0_1.PE1).
GN   Name=lpxC; OrderedLocusNames=NLA_0010;
OS   NEISSERIA LACTAMICA 020-06.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=489653;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEIL0_1.PE1.
CC       Neisseria lactamica ST-640, complete genome.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:E4Z9Q1_NEIL0
CC   -!- FUNCTION: Involved in the biosynthesis of lipid A, a
CC       phosphorylated glycolipid that anchors the lipopolysaccharide to
CC       the outer membrane of the cell (By similarity).
CC   -!- CATALYTIC ACTIVITY: UDP-3-O-(3-hydroxytetradecanoyl)-N-
CC       acetylglucosamine + H(2)O = UDP-3-O-(3-hydroxytetradecanoyl)-
CC       glucosamine + acetate.
CC   -!- PATHWAY: Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid
CC       IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and
CC       UDP-N-acetyl-alpha-D-glucosamine: step 2/6.
CC   -!- SIMILARITY: Belongs to the lpxC family.
CC   -!- GENE_FAMILY: HOG000256663 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4Z9Q1; -.
DR   EMBL; FN995097; CBN86246.1; -; Genomic_DNA.
DR   RefSeq; YP_004047644.1; NC_014752.1.
DR   GeneID; 10007409; -.
DR   GenomeReviews; FN995097_GR; NLA_0010.
DR   KEGG; nla:NLA_0010; -.
DR   GO; GO:0008759; F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity; IEA:HAMAP.
DR   GO; GO:0009245; P:lipid A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00388; LpxC; 1; -.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR004463; UDP-acyl_GlcNac_deAcase.
DR   InterPro; IPR011334; UDP-acyl_GlcNac_deAcase_C.
DR   InterPro; IPR015870; UDP-acyl_N-AcGlcN_deAcase_N.
DR   Gene3D; G3DSA:3.30.1700.10; UDP-acyl_N-AcGlcN_deAcase_C; 1.
DR   Gene3D; G3DSA:3.30.230.20; UDP-acyl_N-AcGlcN_deAcase_N; 1.
DR   Pfam; PF03331; LpxC; 1.
DR   SUPFAM; SSF54211; Ribosomal_S5_D2-typ_fold; 2.
DR   TIGRFAMs; TIGR00325; LpxC; 1.
DR   HOGENOMDNA; NEIL0_1.PE1; -.
KW   Complete proteome; Hydrolase; Lipid A biosynthesis; Lipid synthesis.
SQ   SEQUENCE   307 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLQRTLAKSI GVTGVGLHSG ERVALTLHPA PENSGISFRR TDLDGEMGEQ IKLTPYLIND
     TRLSSTIVTD KGVRVGTIEH IMSALSAYGI DNALIELNAP EIPIMDGSSL PFIYLLQDAG
     VVDQKAQKHF LKILKPVEVK EAGKWVRFTP YDGFKVTLTI EFDHPVFNRS SPTFEIDFAG
     KSYIDEIARA RTFGFMHEVE MMRAHNLGLG GNLNNAIVID DTDILNPEGL RYPDEFVRHK
     ILDAIGDLYI VGHPLIGAFE GYKSGHAINN ALLRAVLADE TAYEWVEFAD NENLPAAFHE
     LNLKKCG
//

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