(data stored in SCRATCH zone)

HOGENOM: NEIL0_1_PE1010

ID   NEIL0_1_PE1010                       STANDARD;      PRT;   197 AA.
AC   NEIL0_1_PE1010; E4ZD52;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=GTP cyclohydrolase-2; EC=3.5.4 25;AltName: Full=GTP
DE   cyclohydrolase II; (NEIL0_1.PE1010).
GN   Name=ribA; OrderedLocusNames=NLA_10600;
OS   NEISSERIA LACTAMICA 020-06.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=489653;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEIL0_1.PE1010.
CC       Neisseria lactamica ST-640, complete genome.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:E4ZD52_NEIL0
CC   -!- FUNCTION: Catalyzes the conversion of GTP to 2,5-diamino-6-
CC       ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and
CC       pyrophosphate (By similarity).
CC   -!- CATALYTIC ACTIVITY: GTP + 3 H(2)O = formate + 2,5-diamino-6-
CC       hydroxy-4-(5-phospho-D-ribosylamino)pyrimidine + diphosphate.
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-
CC       6-(D-ribitylamino)uracil from GTP: step 1/4.
CC   -!- SIMILARITY: Belongs to the GTP cyclohydrolase II family.
CC   -!- GENE_FAMILY: HOG000115442 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4ZD52; -.
DR   EMBL; FN995097; CBN87285.1; -; Genomic_DNA.
DR   RefSeq; YP_004048653.1; NC_014752.1.
DR   GeneID; 10005409; -.
DR   GenomeReviews; FN995097_GR; NLA_10600.
DR   KEGG; nla:NLA_10600; -.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003935; F:GTP cyclohydrolase II activity; IEA:HAMAP.
DR   GO; GO:0008270; F:zinc ion binding; IEA:HAMAP.
DR   GO; GO:0009231; P:riboflavin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00179; RibA; 1; -.
DR   InterPro; IPR000926; GTP_CycHdrlaseII_RibA.
DR   Pfam; PF00925; GTP_cyclohydro2; 1.
DR   TIGRFAMs; TIGR00505; RibA; 1.
DR   HOGENOMDNA; NEIL0_1.PE1010; -.
KW   GTP cyclohydrolase II;
KW   Complete proteome; GTP-binding; Hydrolase; Metal-binding;
KW   Nucleotide-binding; Riboflavin biosynthesis; Zinc.
SQ   SEQUENCE   197 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSELLSYVAS CRLPTEWGVF TMHGFEEAGG QEHVALTVGD FSDGNPVLTR IHSECLTGDA
     LFSRKCDCGP QLEAAMRAVQ AEGRGVIVYL RQEGRGIGLI NKIRAYHLQD QGMDTVEANV
     ALGLPVDARD FRLAQYIYEY LGIRSVKLLT NNPEKIQTLK DAGISVVERI PLHVGENLEN
     ERYLQTKADK LGHLMSE
//

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