(data stored in SCRATCH zone)

HOGENOM: NEIL0_1_PE1011

ID   NEIL0_1_PE1011                       STANDARD;      PRT;   363 AA.
AC   NEIL0_1_PE1011; E4ZD54;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Putative bifunctional 3,4-dihydroxy-2-butanone 4-phosphate
DE   synthase/GTP cyclohydrolase II; (NEIL0_1.PE1011).
GN   Name=ribB; OrderedLocusNames=NLA_10630;
OS   NEISSERIA LACTAMICA 020-06.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=489653;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEIL0_1.PE1011.
CC       Neisseria lactamica ST-640, complete genome.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:E4ZD54_NEIL0
CC   -!- FUNCTION: Catalyzes the conversion of D-ribulose 5-phosphate to
CC       formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity).
CC   -!- CATALYTIC ACTIVITY: D-ribulose 5-phosphate = formate + L-3,4-
CC       dihydroxybutan-2-one 4-phosphate.
CC   -!- COFACTOR: Binds 2 divalent metal cations per subunit. Magnesium or
CC       manganese (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; riboflavin biosynthesis; 2-
CC       hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step
CC       1/1.
CC   -!- GENE_FAMILY: HOG000115440 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4ZD54; -.
DR   EMBL; FN995097; CBN87287.1; -; Genomic_DNA.
DR   RefSeq; YP_004048654.1; NC_014752.1.
DR   GeneID; 10005410; -.
DR   GenomeReviews; FN995097_GR; NLA_10630.
DR   KEGG; nla:NLA_10630; -.
DR   GO; GO:0008686; F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity; IEA:HAMAP.
DR   GO; GO:0003935; F:GTP cyclohydrolase II activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:HAMAP.
DR   GO; GO:0009231; P:riboflavin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00180; RibB; 1; -.
DR   InterPro; IPR017945; DHBP_synth_RibB-like_a/b_dom.
DR   InterPro; IPR000422; DHBP_synthase_RibB.
DR   InterPro; IPR000926; GTP_CycHdrlaseII_RibA.
DR   InterPro; IPR016299; Riboflavin_synth_RibBA.
DR   Gene3D; G3DSA:3.90.870.10; DHBP_synth_RibB-like_a/b_dom; 1.
DR   Pfam; PF00926; DHBP_synthase; 1.
DR   Pfam; PF00925; GTP_cyclohydro2; 1.
DR   PIRSF; PIRSF001259; RibA; 1.
DR   SUPFAM; SSF55821; DHBP_synth_RibB-like_a/b_dom; 1.
DR   TIGRFAMs; TIGR00506; RibB; 1.
DR   HOGENOMDNA; NEIL0_1.PE1011; -.
KW   Complete proteome; Hydrolase; Lyase; Magnesium; Manganese;
KW   Metal-binding; Riboflavin biosynthesis.
SQ   SEQUENCE   363 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSHISPIPEI LADIKAGKMV IITDAEDREN EGDLLMAAQF VTPEAVNFMI KHARGLVCLP
     MAGEMVEKLG LPMMTQKNGA QYGTNFTVSI EAAHGITTGI SAADRALTIQ TAVSPTAKPE
     DIVQPGHIFP LRAQKGGVLV RAGHTEAGVD LAQMNGLIPA AVICEIINDD GTMARMPELM
     KFAEEHKLKI GTIADLIEYR SRTESLLEDM GDAPVQTPWG EFQQHVYVDK LSGETHLALV
     KGTPSADTET LVRVHEPFSV MDFIQANPRH SWSLPKALER VQQAESGVVI LLHRTEDGAS
     LLDRTLPKGA NQAYKWDSKS YGIGAQILAG LNVKKLRVLG QPSSFTGLTG FGLEVVSFEE
     AEK
//

If you have problems or comments...

PBIL Back to PBIL home page