(data stored in SCRATCH3701 zone)

HOGENOM6: NEIL0_1_PE1170

ID   NEIL0_1_PE1170                       STANDARD;      PRT;   912 AA.
AC   NEIL0_1_PE1170; E4ZDL6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (NEIL0_1.PE1170).
GN   Name=gyrA; OrderedLocusNames=NLA_12290;
OS   NEISSERIA LACTAMICA 020-06.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=489653;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEIL0_1.PE1170.
CC       Neisseria lactamica ST-640, complete genome.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:E4ZDL6_NEIL0
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4ZDL6; -.
DR   EMBL; FN995097; CBN87450.1; -; Genomic_DNA.
DR   RefSeq; YP_004048813.1; NC_014752.1.
DR   GeneID; 10006855; -.
DR   GenomeReviews; FN995097_GR; NLA_12290.
DR   KEGG; nla:NLA_12290; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; NEIL0_1.PE1170; -.
DR   PRODOM; NEIL0_1_PE1170.
DR   SWISS-2DPAGE; NEIL0_1_PE1170.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   912 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDATIRHDH KFALETLPVS LEDEMRKSYL DYAMSVIVGR ALPDVRDGLK PVHRRVLYAM
     HELKNNWNAA YKKSARIVGD VIGKYHPHGD TAVYDTIVRM AQNFAMRYVL IDGQGNFGSV
     DGLAAAAMRY TEIRMAKISH EMLADIEEET VNFGPNYDGS EHEPLVLPTR FPALLVNGSS
     GIAVGMATNI PPHNLSDTIN ACLRLLDAPE TEIDELIDII QAPDFPTGAT IYGLSGVREG
     YKTGRGRVVI RAKTHTEPIG KNGEREAIVI DEIPYQVNKA KLVEKIGELV REKTLEGISE
     LRDESDKSGM RVVIELKRNE NAEVVLNQLY KLTQLQDSFG INMVVLVDGQ PRLLNLKQIL
     SEFLRHRREV VTRRTLFRLK KARHEGHIAE GKAVALSNID EIIRLIKESP NAAEAKEKLL
     ARPWRSSLVE EMLTRSGLDL EMMRPEGLAA NIGLKEQGYY LSEIQADAIL RMSLRNLTGL
     DREEIVESYK NLMGKIIDFV DILSKPERIT RIIRDELEEI KTNYGDERLS EINPFGGDIA
     DEDLIPQREM VVTLTHGGYI KTQPTTDYQA QRRGGRGKQA AATKDEDFIE TLFVANTHDY
     LMCFTNLGKC HWIKVYKLPE GGRNSRGRPI NNVIQLEEGE KVSAILAVRE FPEDQYVFFA
     TAQGIVKKVR LSAFKNVRAQ GIKAIALKEG DSLIGAAQTG GSDDIMLFSN LGKAIRFNEY
     WEKSGNGEAE DADSETSDGI EDENADSENA LPGGKYGVRP SGRGSGGMRG MRLPADGKIV
     SLITFAPEAG ESGLQVLTAT ANGYGKRTPI ADYSRKNKGG QGNIAINTGE RNGDLVAATL
     VGETDDLMLI TSGGVLIRTK VEQIRETGRA AAGVKLINLD EGETLVSLER VAEEETETDM
     PETEAGTSPE TN
//

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