(data stored in SCRATCH3701 zone)

HOGENOM6: NEIMF_1_PE1188

ID   NEIMF_1_PE1188                       STANDARD;      PRT;   916 AA.
AC   NEIMF_1_PE1188; A1KUK5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (NEIMF_1.PE1188).
GN   Name=gyrA; OrderedLocusNames=NMC1320;
OS   NEISSERIA MENINGITIDIS FAM18.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=272831;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEIMF_1.PE1188.
CC       Neisseria meningitidis FAM18, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A1KUK5_NEIMF
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A1KUK5; -.
DR   EMBL; AM421808; CAM10548.1; -; Genomic_DNA.
DR   RefSeq; YP_975334.1; NC_008767.1.
DR   ProteinModelPortal; A1KUK5; -.
DR   SMR; A1KUK5; 38-533.
DR   STRING; A1KUK5; -.
DR   EnsemblBacteria; EBNEIT00000006893; EBNEIP00000006662; EBNEIG00000006893.
DR   GeneID; 4676464; -.
DR   GenomeReviews; AM421808_GR; NMC1320.
DR   KEGG; nmc:NMC1320; -.
DR   NMPDR; fig|487.2.peg.619; -.
DR   eggNOG; COG0188; -.
DR   GeneTree; EBGT00050000021399; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; A1KUK5; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; NEIMF_1.PE1188; -.
DR   PRODOM; NEIMF_1_PE1188.
DR   SWISS-2DPAGE; NEIMF_1_PE1188.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   916 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDATIRHDH KFALETLPVS LEDEMRKSYL DYAMSVIVGR ALPDVRDGLK PVHRRVLYAM
     HELKNNWNAA YKKSARIVGD VIGKYHPHGD TAVYDTIVRM AQNFAMRYVL IDGQGNFGSV
     DGLAAAAMRY TEIRMAKISH EMLADIEEET VNFGPNYDGS EHEPLVLPTR FPTLLVNGSS
     GIAVGMATNI PPHNLSDTVN ACLRLLDAPD TEIDELIDII QAPDFPTGAT IYGLSGVREG
     YKTGRGRVVM RGKTHIEPIG RNGEREAIVI DEIPYQVNKA KLVEKIGDLV REKTLEGISE
     LRDESDKSGM RVVIELKRNE NAEVVLNQLY KLTPLQDSFG INMVVLVDGQ PRLLNLKQIL
     SEFLRHRREV VTRRTLFRLK KARHEGHIAE GKAVALSNID EIIKLIKESP NAAEAKDKLL
     AHPWRSSLVE EMLTRSGLDL EMMRPEGLAA NIGLKEQGYY LSEIQADAIL RMSLRNLTGL
     DQEEIVESYK NLMGKIIDFV DILSKPERIT QIIRDELEEI KTNYGDERRS EINPFGGDIA
     DEDLIPQREM VVTLTHGGYI KTQPTTDYQA QRRGGRGKQA AATKDEDFIE TLFVANTHDY
     LMCFTNLGKC HWIKVYKLPE GGRNSRGRPI NNVIQLEEGE KVSAILAVRE FPEDQYVFFA
     TAQGMVKKVQ LSAFKNVRAQ GIKAIALKEG DYLVGAAQTG GADDIMLFSN LGKAIRFNEY
     WEKSGNDEAE DADIETEISD GIEDETADSE NALPSGKHGV RPSGRGSGGL RGMRLPADGK
     IVSLITFAPE TEESGLQVLT ATANGYGKRT PIADYSRKNK GGQGNIAINT GERNGDLVAA
     TLVGETDDLM LITSGGVLIR TKVEQIRETG RAAAGVKLIN LDEGETLVSL ERVAEDESEL
     SDASVISNVT EPEVEN
//

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