(data stored in ACNUC7421 zone)

HOGENOM: NEUCR_2_PE40

ID   NEUCR_2_PE40                         STANDARD;      PRT;   388 AA.
AC   NEUCR_2_PE40; Q7S4G7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (NEUCR_2.PE40).
GN   Name=mri-1; ORFNames=NCU02226;
OS   NEUROSPORA CRASSA.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=5141;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NEUCR_2.PE40.
CC       Neurospora crassa supercontig 7.10 EF1 full sequence 1..946518 annotate
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:MTNA_NEUCR
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Neurospora_crassa;EFNCRG00000003080;EFNCRT00000003083;EFNCRP00000003083.
DR   UniProtKB/Swiss-Prot; Q7S4G7; -.
DR   EMBL; AABX02000010; EAA30403.1; -; Genomic_DNA.
DR   RefSeq; XP_959639.1; XM_954546.1.
DR   UniGene; Ncr.25291; -.
DR   ProteinModelPortal; Q7S4G7; -.
DR   STRING; Q7S4G7; -.
DR   EnsemblFungi; EFNCRT00000003083; EFNCRP00000003083; EFNCRG00000003080.
DR   GeneID; 3875786; -.
DR   KEGG; ncr:NCU02226; -.
DR   NMPDR; fig|5141.1.peg.8935; -.
DR   eggNOG; fuNOG06631; -.
DR   GeneTree; EFGT00050000003245; -.
DR   OMA; RPRNQGA; -.
DR   OrthoDB; EOG4S1XGM; -.
DR   PhylomeDB; Q7S4G7; -.
DR   GO; GO:0005737; C:cytoplasm; ISS:RefGenome.
DR   GO; GO:0005634; C:nucleus; ISS:RefGenome.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; ISS:RefGenome.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; ISS:RefGenome.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; NEUCR_2.PE40; -.
KW   EFNCRG00000003080g.scaffold_90100000011;
KW   Q7S4G7;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus; Reference proteome.
SQ   SEQUENCE   388 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSALEAIKYS RGKLEVLDQL RLPHEHHYDE VSTSEEAFDC IKAMRVRGAP AIAIVAALAA
     SVELHNGSCT ATGTEDVIKY IDSRLDYLYE SRPTAVDLGN AVRLLKKTVR GVKTEGLTDA
     EAKEAIIKAF IEASEEILAK DLKTNKSIGA FGAKWLQEQY KITDDSKITV MTHCNTGSLA
     TSGHGTALGI IRTLRDEGLL RHAYCTETRP YNQGSRLTAF ELVHEGIPAT LVTDSMAAAL
     FRLRKAEENI AAVIVGADRV VRNGDTANKI GTYQLAVLAK HHGIKFMVAA PTTSIDVDTE
     TGDDIEIEQR KREELTQISG AVVNADGSID TSKSVRVAIA DQRIGVWNPG FDVTPHEYID
     AIVTEKGTVV KGEDGKFHFE DLMPERFQ
//

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