(data stored in SCRATCH3701 zone)

HOGENOM6: NITHN_2_PE2482

ID   NITHN_2_PE2482                       STANDARD;      PRT;   846 AA.
AC   NITHN_2_PE2482; D5BWP7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (NITHN_2.PE2482).
GN   OrderedLocusNames=Nhal_2628;
OS   NITROSOCOCCUS HALOPHILUS NC4.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Chromatiaceae; Nitrosococcus.
OX   NCBI_TaxID=472759;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NITHN_2.PE2482.
CC       Nitrosococcus halophilus Nc4 chromosome, complete genome.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:D5BWP7_NITHN
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D5BWP7; -.
DR   EMBL; CP001798; ADE15704.1; -; Genomic_DNA.
DR   RefSeq; YP_003528091.1; NC_013960.1.
DR   GeneID; 8917628; -.
DR   GenomeReviews; CP001798_GR; Nhal_2628.
DR   KEGG; nhl:Nhal_2628; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; NITHN_2.PE2482; -.
DR   PRODOM; NITHN_2_PE2482.
DR   SWISS-2DPAGE; NITHN_2_PE2482.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   846 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEEIAQEVFP VNIEDEMKQS YLDYAMSVIV GRALPDARDG LKPVHRRVLY AMQELGNDWN
     KPYKKSARVV GDVIGKYHPH GDAAVYDAIV RMAQPFSMRY PLVDGQGNFG SIDGDPPAAM
     RYTEVRMAKI AHELLADLNK ETVDFVPNYD ESEYEPAVLP TRIPNLLANG SSGIAVGMAT
     NIPPHNLGEV LSACIALIDD PSLDIAGIMA HIPGPDFPTA GIVNGSRGIQ EAYLTGRGRI
     FLRARTHVET DEASGRQSII VTELPYMVNK ARLLEKIGEL VKEKKIEGIV GLRDESDKEG
     MRMVVELRRN EMPEVVLNHL YLHTQLQTVF GINMVALVDG QPQVLNLKLA LEAFLRHRQE
     VVTRRTVFEL RKARERAHVL EGLAIALTNI DPVIALIKAS SSPSEARDGL IARSWPPGVV
     IDMLQRAGAE SSRPEGLEAV YGLQEGGYRL SPAQAQAILD MRLHRLTGLE QGKIIDEYQQ
     VIELISELLE ILANPERLMA VIREELVEMR QQYGELRRTE IQYNHVDLRL EDLIQEENVV
     VTLSHTGYAK YQALDAYRSQ KRGGKGKSAT AMKEEDFIDK LFIANTHDTL LCFSSRGKVY
     WKKVYELPQG TRTARGKPIV NLLPLEEGER INTVLPIREF EEGKYVFMVT ASGVVKKTSL
     AVFSRPRPSG IIALELREGD QLVGADLTDG EQEIMLFSSG GKVIRFSEQK VRPMGRTARG
     VKGMELPPEH RVIALIIARN GTILTATELG YGKRTAIAEY RLQGRGGQGI ISIQTTPRNG
     QVVGAVQVEE EDEIVLITNR GTLIRTPVCD ISLMGRNTQG VKLINLLEGE RLVGVERIVE
     DGEAAI
//

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