(data stored in SCRATCH3701 zone)

HOGENOM6: NITMU_1_PE2172

ID   NITMU_1_PE2172                       STANDARD;      PRT;   893 AA.
AC   NITMU_1_PE2172; Q2Y6Z0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (NITMU_1.PE2172).
GN   OrderedLocusNames=Nmul_A2189;
OS   NITROSOSPIRA MULTIFORMIS ATCC 25196.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=323848;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NITMU_1.PE2172.
CC       Nitrosospira multiformis ATCC 25196 chromosome, complete sequence.
CC       Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:Q2Y6Z0_NITMU
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2Y6Z0; -.
DR   EMBL; CP000103; ABB75481.1; -; Genomic_DNA.
DR   RefSeq; YP_412873.1; NC_007614.1.
DR   ProteinModelPortal; Q2Y6Z0; -.
DR   SMR; Q2Y6Z0; 62-556, 571-877.
DR   STRING; Q2Y6Z0; -.
DR   GeneID; 3786214; -.
DR   GenomeReviews; CP000103_GR; Nmul_A2189.
DR   KEGG; nmu:Nmul_A2189; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q2Y6Z0; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; NMUL323848:NMUL_A2189-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; NITMU_1.PE2172; -.
DR   PRODOM; NITMU_1_PE2172.
DR   SWISS-2DPAGE; NITMU_1_PE2172.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   893 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLKWGALYAD IRKEIYPRYV PVPASSCPPS KVMDQFAKET LQISLEEEMR RSYLDYAMSV
     IVGRALPDVR DGLKPVHRRV LFAMHELSND WNRPYKKSAR VVGDVIGKYH PHGDTAVYDT
     IVRMAQNFSL RYMLVDGQGN FGSVDGDNPA AMRYTEIRMS RIAHEMLADL DKETVDFGPN
     YDGTEKEPLI LPTKIPNLLI NGSSGIAVGM ATNIPPHNLN EVTDACLALL KNPEIAIEDL
     IELIPGPDFP TAALIYGVTG VKEGYRTGRG RVIMRARTHF EDMEKGGGRQ SIVIDELPYQ
     VNKANLLIRI GELVRDKKIE GISDLRDESD KSGMRVVIEL RRNEVPEVVL NNLYKETQMQ
     DTFGMNMVAL LDGQPRLLNL KQMLEAFLRH RREVVTRRSV FELKKARERG HVLEGLAVAL
     SNVDEVIALI KAAQTPAAAK EALMSRVWRS RLVEQMLARA AVDAKQFRPE GLAPEYGLFD
     DGYHLSDGQA QAILELRLQR LTGLEQDKIV SEYRDVMERI ADLLDILARP ERITAIITEE
     LVAMKQQFGD KRRSEIVINT QDLSMEDLIA SEDVVVTLSH NGYIKSQPLD DYRAQKRGGR
     GKQATGTKDD DFIDNLFIAN THDYILCFSS RGRVYWIKVY SVPQGGRASR GRPIVNLMQL
     EYGEKINAVL PIKTFDDNRY VFMATSLGTV KKTPLSEFSR PRASGIIAVG LDEDDFLIGV
     ALTEGKHDVM LFSDGGKAVR FDENDVRPMG RGARGVRGMT LGKGQKVISL LVAESEEQAV
     LTATENGYGK RTPISEYTRH GRGSQGMIAI KTTQRNGKVV GARLVREDDE IMLITTGGVL
     IRTRVKEVRE MSRATQGVIL INLDEGEKLA GLERVVETDE APGLGEGLAT DLP
//

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