(data stored in SCRATCH3701 zone)

HOGENOM6: NOCSJ_2_PE7

ID   NOCSJ_2_PE7                          STANDARD;      PRT;   922 AA.
AC   NOCSJ_2_PE7; A1SCM2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (NOCSJ_2.PE7).
GN   Name=gyrA; OrderedLocusNames=Noca_0007;
OS   NOCARDIOIDES SP. JS614.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Propionibacterineae; Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=196162;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NOCSJ_2.PE7.
CC       Nocardioides sp. JS614, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:GYRA_NOCSJ
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A1SCM2; -.
DR   EMBL; CP000509; ABL79557.1; -; Genomic_DNA.
DR   RefSeq; YP_921244.1; NC_008699.1.
DR   ProteinModelPortal; A1SCM2; -.
DR   STRING; A1SCM2; -.
DR   GeneID; 4598358; -.
DR   GenomeReviews; CP000509_GR; Noca_0007.
DR   KEGG; nca:Noca_0007; -.
DR   eggNOG; COG0188; -.
DR   OMA; QRENVIV; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; NSP35761:NOCA_0007-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; NOCSJ_2.PE7; -.
DR   PRODOM; NOCSJ_2_PE7.
DR   SWISS-2DPAGE; NOCSJ_2_PE7.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   922 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTETPTDGGS TPPSDGGGPG GRIEPVELQT SMQRAYIDYA MAVIVGRALP DVRDGLKPVH
     RRVLYAMYDG GYRPDRGFSK CSRVVGDVMG QYHPHGDTAI YDTLVRLAQP WVMRAPLIHG
     QGNFGSPGND SAAAMRYTEC RMAPLAMEMV RDINEDTVDF QPNYDGRSQE PVVLPARFPN
     LLVNGSAGIA VGMATNIPPH NLREVAEGAR WALEHPDATR EELQDALIER IKGPDFPNGA
     LIVGRQGIEQ AYRTGRGSIT QRAVIEVDED AKGRTNLVIT ELPYMVNPDN LALKIAELAD
     SGKVQGISDV RDDTSDRTGQ RLVVVLKRDA VARVVLNNLL KHTELQTNFS ANMLALVDGV
     PRTLAIDQFI SNWVTHQIDV IRRRTEYRLA EAEKRAHVLR GLVKALDMLD EVIALIRRSP
     DVAEAREGLI ALLDIDEVQA TAILDMQLRQ LAALQRQKII DDLAEIEARI ADLKDILANV
     ARQRQIVADE LAEIVERYGD DRRSQIIAAD GDLSMEDLIP DEELVVSITR GGYAKRTRAD
     QYRTQRRGGK GVRGATLRGD DVVEHFIATT NHHWLLFFTT AGRVYRTKAY NLPEASRDAK
     GGHVAGLLSF QPDENIAQVL AIRDYDQAPY LVLATRDGLV KKTRLGDYNS PRQAGVIAIN
     FRSEDDELIG AELVNPEDHI LLVSRKGQSV RFQADDSQLR PMGRATGGVT GMKFRDGDSL
     LSMSVIRAAQ VEAEEAAEAS GESVEEMAET RGQWFGLHPQ YVFTITDGGF AKRTQIPEYR
     VQSRGGIGIR AMKLANEDRG ELVGAFIVED GDEILSITSG GQVVRSPIDE NFRPTGRSTM
     GVKFVTPKKG DSVAVVARSV EANGDDELDE LDESALDEGG AEGGEVDESA DAGTDATIDG
     SAASDVARTE GDTEPDPGES DG
//

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