(data stored in ACNUC9435 zone)

HOGENOM: NOVAD_1_PE1002

ID   NOVAD_1_PE1002                       STANDARD;      PRT;   197 AA.
AC   NOVAD_1_PE1002; Q2G9M2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD;
DE   EC=4.2.1 19; (NOVAD_1.PE1002).
GN   Name=hisB; OrderedLocusNames=Saro_1006;
OS   NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=279238;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NOVAD_1.PE1002.
CC       Novosphingobium aromaticivorans DSM 12444, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:HIS7_NOVAD
CC   -!- CATALYTIC ACTIVITY: D-erythro-1-(imidazol-4-yl)glycerol 3-
CC       phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-histidine biosynthesis; L-
CC       histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the imidazoleglycerol-phosphate dehydratase
CC       family.
CC   -!- GENE_FAMILY: HOG000228064 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2G9M2; -.
DR   EMBL; CP000248; ABD25451.1; -; Genomic_DNA.
DR   RefSeq; YP_496285.1; NC_007794.1.
DR   ProteinModelPortal; Q2G9M2; -.
DR   SMR; Q2G9M2; 2-183.
DR   STRING; Q2G9M2; -.
DR   GeneID; 3915788; -.
DR   GenomeReviews; CP000248_GR; Saro_1006.
DR   KEGG; nar:Saro_1006; -.
DR   eggNOG; COG0131; -.
DR   OMA; RHGLFDL; -.
DR   PhylomeDB; Q2G9M2; -.
DR   ProtClustDB; PRK00951; -.
DR   BioCyc; NARO279238:SARO_1006-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004424; F:imidazoleglycerol-phosphate dehydratase activity; IEA:EC.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00076; HisB; 1; -.
DR   InterPro; IPR000807; ImidazoleglycerolP_deHydtase.
DR   InterPro; IPR020565; ImidazoleglycerP_deHydtase_CS.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   PANTHER; PTHR23133:SF2; Imidazole-GPD; 1.
DR   Pfam; PF00475; IGPD; 1.
DR   SUPFAM; SSF54211; Ribosomal_S5_D2-typ_fold; 2.
DR   PROSITE; PS00954; IGP_DEHYDRATASE_1; 1.
DR   PROSITE; PS00955; IGP_DEHYDRATASE_2; 1.
DR   HOGENOMDNA; NOVAD_1.PE1002; -.
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm;
KW   Histidine biosynthesis; Lyase.
SQ   SEQUENCE   197 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRTGSITRKT EETDIAVSVN LDGTGTYKVD TGIGFLDHMI EQFSRHSLID IECRVKGDLH
     VDQHHTTEDS AIALGQAISQ ALGDKKGITR YGHTYSPMDE ALCRVALDIS GRPVLVWKAA
     FTQPRLGEMD TELFEHWFQS ISQAAGITLH IESLYGSNNH HIIEGIYKGF ARAMRAAIAI
     DPRKADAVPS TKGILGG
//

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