(data stored in SCRATCH3701 zone)

HOGENOM6: NOVAD_1_PE1909

ID   NOVAD_1_PE1909                       STANDARD;      PRT;   908 AA.
AC   NOVAD_1_PE1909; Q2G715;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (NOVAD_1.PE1909).
GN   OrderedLocusNames=Saro_1918;
OS   NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=279238;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS NOVAD_1.PE1909.
CC       Novosphingobium aromaticivorans DSM 12444, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q2G715_NOVAD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2G715; -.
DR   EMBL; CP000248; ABD26358.1; -; Genomic_DNA.
DR   RefSeq; YP_497192.1; NC_007794.1.
DR   ProteinModelPortal; Q2G715; -.
DR   SMR; Q2G715; 41-525.
DR   STRING; Q2G715; -.
DR   GeneID; 3917141; -.
DR   GenomeReviews; CP000248_GR; Saro_1918.
DR   KEGG; nar:Saro_1918; -.
DR   NMPDR; fig|48935.1.peg.889; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q2G715; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; NOVAD_1.PE1909; -.
DR   PRODOM; NOVAD_1_PE1909.
DR   SWISS-2DPAGE; NOVAD_1_PE1909.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   908 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDDTTIIDP PAPAPEGEFQ RIDIVDEMKT SYLDYAMSVI VSRALPDVRD GLKPVHRRIL
     WTSHENGFVS TKAYRKSARI VGDAMGKYHP HGDAAIYDAL ARMTQDWSMR LPLIDGQGNF
     GSMDPDPPAS MRYTEARLAK VADSLLADID KDTVDFQPNY DGAEHEPQVL PARFPNLLVN
     GAGGIAVGMA TNIPPHNLGE VIDACLAYMD NPLVTIDELI QIIPGPDFPT APLILGTAGA
     RKAYHEGRGS IIMRARHQIE EGRGDRRSIV LTSIPYQVGK SGLVEKIAEA AKDKRIEGIS
     DIRDESNREG VRVVIDLKRD ATPEVVLNQL WRNTPAQSSF PANMLAIRGG RPEVLNLKDI
     IESFVRFREE VITRRTKFEL NKARDRAHIL LGLVIAVTNL DEVVRIIRGS PNPAVARETL
     LAREWPMGEI APYIRLVEAI EDAGVAEAAT YRLSEIQVRA ILDLRLHRLT ALGRDEIGDE
     LEGLAKAIAE YLSILADREK LFGVMRQELL EVQHAFATPR KSEITAPADG IEDEDLIERE
     DMVVTITLDG YIKRTPLSTF RAQNRGGKGR SGMATKDEDA VATMFVTSTH TPVLFFSTAG
     KVYRLKVWRL PEGGPTTRGR PVVNMLPALD KDETIATVLP LPEDEAEWGK LSVVFATAKG
     NVRRNSMDAF ANIPSNGKFA MKFEEDSADR LIGVALLEAS DDVLLATRSG KAIRFAGDEV
     REFTSRTSTG VRGMTLKGDD EVISLSILHR VGTTPDERED YVRFAPWKGE KEGEPALSAE
     RYAELQAREQ FILTVCANGY GKLSSAYEYR RTGRGGQGIT NIDNIGRNGP VVASFPATQA
     DQLMLVTDQA KLIRLPLDSL RVIGRGSAGV RLFNVSGGEH VVSAVRLAEE EGAESDDVGA
     VPDEGTAE
//

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