(data stored in ACNUC10243 zone)

HOGENOM: PANTR21_32_PE9

ID   PANTR21_32_PE9                       STANDARD;      PRT;   320 AA.
AC   PANTR21_32_PE9; A5A6H4; Q564E0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP
DE   A1;AltName: Full=Helix-destabilizing protein;AltName:
DE   Full=Single-strand-binding protein;AltName: Full=hnRNP core protein A1;
DE   (PANTR21_32.PE9).
GN   Name=HNRNPA1; Synonyms=HNRPA1;
OS   PAN TROGLODYTES.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Homininae; Pan.
OX   NCBI_TaxID=9598;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PANTR21_32.PE9.
CC       Pan troglodytes chromosome 21 CHIMP2.1 partial sequence 30861925..31861
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:ROA1_PANTR
CC   -!- FUNCTION: Involved in the packaging of pre-mRNA into hnRNP
CC       particles, transport of poly(A) mRNA from the nucleus to the
CC       cytoplasm and may modulate splice site selection (By similarity).
CC   -!- SUBUNIT: Identified in the spliceosome C complex. Identified in a
CC       mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG,
CC       HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU,
CC       HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4,
CC       PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2,
CC       YBX1 and untranslated mRNAs. Interacts with SEPT6 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By
CC       similarity). Note=Localized in cytoplasmic mRNP granules
CC       containing untranslated mRNAs. Shuttles continuously between the
CC       nucleus and the cytoplasm along with mRNA. Component of
CC       ribonucleosomes (By similarity).
CC   -!- PTM: Sumoylated (By similarity).
CC   -!- SIMILARITY: Contains 2 RRM (RNA recognition motif) domains.
CC   -!- GENE_FAMILY: HOG000234442 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Pan_troglodytes;ENSPTRG00000028756;ENSPTRT00000010845;ENSPTRP00000048316.
DR   EMBL; AB222102; - ;
DR   EMBL; AL954201; - ;
DR   UniProtKB/Swiss-Prot; A5A6H4; Q564E0; -.
DR   EMBL; AB222102; BAF62347.1; -; mRNA.
DR   EMBL; AL954201; CAH18571.1; -; Genomic_DNA.
DR   RefSeq; NP_001091892.1; NM_001098422.2.
DR   RefSeq; NP_001184040.1; NM_001197111.1.
DR   RefSeq; XP_003318234.1; XM_003318186.1.
DR   UniGene; Ptr.6288; -.
DR   UniGene; Ptr.6435; -.
DR   ProteinModelPortal; A5A6H4; -.
DR   SMR; A5A6H4; 8-190.
DR   GeneID; 100615525; -.
DR   GeneID; 739306; -.
DR   GeneID; 747284; -.
DR   KEGG; ptr:739306; -.
DR   KEGG; ptr:747284; -.
DR   CTD; 144983; -.
DR   eggNOG; maNOG13969; -.
DR   GeneTree; ENSGT00550000074566; -.
DR   InParanoid; A5A6H4; -.
DR   OrthoDB; EOG4HQDKF; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR021662; HnRNPA1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait.
DR   InterPro; IPR000504; RRM_dom.
DR   Gene3D; G3DSA:3.30.70.330; a_b_plait_nuc_bd; 1.
DR   Pfam; PF11627; HnRNPA1; 1.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   PROSITE; PS50102; RRM; 2.
DR   HOGENOMDNA; PANTR21_32.PE9; -.
KW   ENSPTRG00000028756-2caffold_90100000011;
KW   ROA1_PANTR; AB222102; AL954201;
KW   Acetylation; Cytoplasm; Isopeptide bond; Methylation; mRNA processing;
KW   mRNA splicing; mRNA transport; Nucleus; Phosphoprotein; Repeat;
KW   Ribonucleoprotein; RNA-binding; Spliceosome; Transport;
KW   Ubl conjugation.
SQ   SEQUENCE   320 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSKSESPKEP EQLRKLFIGG LSFETTDESL RSHFEQWGTL TDCVVMRDPN TKRSRGFGFV
     TYATVEEVDA AMNARPHKVD GRVVEPKRAV SREDSQRPGA HLTVKKIFVG GIKEDTEEHH
     LRDYFEQYGK IEVIEIMTDR GSGKKRGFAF VTFDDHDSVD KIVIQKYHTV NGHNCEVRKA
     LSKQEMASAS SSQRGRSGSG NFGGGRGGGF GGNDNFGRGG NFSGRGGFGG SRGGGGYGGS
     GDGYNGFGND GSNFGGGGSY NDFGNYNNQS SNFGPMKGGN FGGRSSGPYG GGGQYFAKPR
     NQGGYGGSSS SSSYGSGRRF
//

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