(data stored in SCRATCH3701 zone)

HOGENOM6: PEDHD_1_PE2141

ID   PEDHD_1_PE2141                       STANDARD;      PRT;   869 AA.
AC   PEDHD_1_PE2141; C6XXU9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (PEDHD_1.PE2141).
GN   OrderedLocusNames=Phep_2163;
OS   PEDOBACTER HEPARINUS DSM 2366.
OC   Bacteria; Bacteroidetes; Sphingobacteria; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=485917;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PEDHD_1.PE2141.
CC       Pedobacter heparinus DSM 2366, complete genome.
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:C6XXU9_PEDHD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C6XXU9; -.
DR   EMBL; CP001681; ACU04367.1; -; Genomic_DNA.
DR   RefSeq; YP_003092429.1; NC_013061.1.
DR   STRING; C6XXU9; -.
DR   GeneID; 8253269; -.
DR   GenomeReviews; CP001681_GR; Phep_2163.
DR   KEGG; phe:Phep_2163; -.
DR   OMA; TGRGRIY; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; PEDHD_1.PE2141; -.
DR   PRODOM; PEDHD_1_PE2141.
DR   SWISS-2DPAGE; PEDHD_1_PE2141.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   869 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAEDLENQEN DKIIRIDIDE QMRSAYIDYS MSVIVSRALP DVRDGLKPVH RRVLYGMLDL
     GLANNKPYKK SARIVGEVLG KYHPHGDASV YNTMVRMAQE WSLRYLMVEG QGNYGSIDGD
     SPAAMRYTEA RFQKIAEDML ADINKDTVDF QLNFDDSLQE PTVLPSKVPN LLINGSSGIA
     VGMATNMPPH NITETINATI AYIDNNEITI AELMKFIKAP DFPTGAIIYG YTGVQEAFET
     GRGRIVMRAK AEIEAAKDRE VIIVTEIPYQ VNKAQMIERT AELVGEKKLE GISNIKDESN
     KDGIRIVYEI KRDANASIVL NNLFKQTALQ TSFSVNNIAL VKGRPQLLNL RDLIHYFVEH
     RHEVVVRRTK FELAEAKKRA HILEGLLIAL DHLDEVIKLI RSSDTPEDAR TGLMEKFGLS
     DIQARAILDM TLRRLTGLER DKIKDEYNEL MKTIEYLQSI LDDESKRMQI IKDELTEMKE
     KYGDERRTTI VHSAEDMSME DFIEDEEVVI TISHEGYIKR TPATEYRTQG RGGKGSKGSD
     SRNEDFIEHL LIASNHNYML FFTETGRCFW LRVYEIPEGT RLSKGRAIQN IINIPKEEKI
     KAFIKVKNLK DQEYLENNYI IMCTKKGTIK KTSLEAYSRP RVNGINAINI NEGDQLLEAS
     LTTGSSEIVM ALRSGRAIRF NEEKVRPMGR TATGVRGVTL AHEKDEVVGM IAVDDPGATI
     LVVSEKGYGK RTDIEDYRVT NRGGKGVKTI NVTDKTGNLV AIKSVTDADD LMIINKSGIV
     IRIVVSELRV MGRATQGVRL INLKGNDEIA SVARIEHEDE EVEEAESHVV VDGEPAGEVE
     EEITEEPTAE EENEEEGDAD EDASEEEDN
//

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