(data stored in ACNUC7421 zone)

HOGENOM: PELTS_1_PE1007

ID   PELTS_1_PE1007                       STANDARD;      PRT;   303 AA.
AC   PELTS_1_PE1007; A5D3I0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylenetetrahydrofolate reductase; EC=1.5.1 20;
DE   (PELTS_1.PE1007).
GN   Name=MetF; OrderedLocusNames=PTH_1006;
OS   PELOTOMACULUM THERMOPROPIONICUM SI.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Peptococcaceae;
OC   Pelotomaculum.
OX   NCBI_TaxID=370438;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PELTS_1.PE1007.
CC       Pelotomaculum thermopropionicum SI chromosome, complete genome.
CC       annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:A5D3I0_PELTS
CC   -!- CATALYTIC ACTIVITY: 5-methyltetrahydrofolate + NAD(P)(+) = 5,10-
CC       methylenetetrahydrofolate + NAD(P)H.
CC   -!- COFACTOR: FAD (By similarity).
CC   -!- SIMILARITY: Belongs to the methylenetetrahydrofolate reductase
CC       family.
CC   -!- GENE_FAMILY: HOG000016467 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A5D3I0; -.
DR   EMBL; AP009389; BAF59187.1; -; Genomic_DNA.
DR   RefSeq; YP_001211556.1; NC_009454.1.
DR   ProteinModelPortal; A5D3I0; -.
DR   STRING; A5D3I0; -.
DR   GeneID; 5139626; -.
DR   GenomeReviews; AP009389_GR; PTH_1006.
DR   KEGG; pth:PTH_1006; -.
DR   eggNOG; COG0685; -.
DR   OMA; GIITQPV; -.
DR   ProtClustDB; CLSK941296; -.
DR   BioCyc; PTHE370438:PTH_1006-MONOMER; -.
DR   GO; GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
DR   GO; GO:0006555; P:methionine metabolic process; IEA:InterPro.
DR   InterPro; IPR003171; Mehydrof_redctse.
DR   Pfam; PF02219; MTHFR; 1.
DR   HOGENOMDNA; PELTS_1.PE1007; -.
KW   5,10-methylenetetrahydrofolate reductase;
KW   Complete proteome; FAD; Flavoprotein; Oxidoreductase.
SQ   SEQUENCE   303 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNAGSRLEQV LKSGRLAVTA EISPPKHSSP EGIINLARIL KDWVDAANIT DCQAAVVRMS
     SISAGIHILQ NGLEPVIQVT CRDRNRIAIQ SDLLGAYSLG MRNLLCLSGD HQSFGNHPAA
     KNVYDVDSVQ LIQLVRRMRD ERKFFSGEEI KKCEPRFFIG AVANPFADPF ELQVDRLEKK
     IEAGAEFIQT QCIYDMERFA RFMEVCVRRG LHERAYILAG LTPIKGLRSV SYMRTIPGIT
     VPDEIVSRVK NARDQKAEGI NICIEQINYI RKNIKGISGI HLMAIAWEEI VPEIVKRAGL
     RRE
//

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