(data stored in ACNUC7421 zone)

HOGENOM: PENCW_11_PE86

ID   PENCW_11_PE86                        STANDARD;      PRT;   382 AA.
AC   PENCW_11_PE86; B6H5R4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (PENCW_11.PE86).
GN   Name=mri1; ORFNames=Pc14g00860;
OS   PENICILLIUM CHRYSOGENUM WISCONSIN 54-1255.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae;
OC   Penicillium; Penicillium chrysogenum complex.
OX   NCBI_TaxID=500485;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PENCW_11.PE86.
CC       Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-
CC       1255) contig Pc00c14, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:MTNA_PENCW
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B6H5R4; -.
DR   EMBL; AM920429; CAP74227.1; -; Genomic_DNA.
DR   RefSeq; XP_002560080.1; XM_002560034.1.
DR   ProteinModelPortal; B6H5R4; -.
DR   STRING; B6H5R4; -.
DR   GeneID; 8310322; -.
DR   GenomeReviews; AM920429_GR; mri1.
DR   KEGG; pcs:Pc14g00860; -.
DR   OrthoDB; EOG4S1XGM; -.
DR   BioCyc; PCHR:PC14G00860-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; PENCW_11.PE86; -.
KW   CAP74227.100028832-2caffold_90100000011;
KW   Methylthioribose-1-phosphate isomerase ;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus.
SQ   SEQUENCE   382 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLQAIKFSKG NLEILDQLQL PFVEEYIPIR TTEDGWHAIK DMKVRGAPAI AIVAMLALAA
     ELTSAVDSDK LSQSPEEVCQ YITEKLAYLV TSRPTAVNLA DAARKLEAVV TDCTKAPGST
     GHEVATAFIK AAEDMMGKDL EDNKRIGHNG AEWIAIHAAK GNSEVAVLTH CNTGSLATSG
     YGTALGVVRS LAEKNTLRHA YCTETRPYNQ GSRLTAFELV HDKIPATLIT DSMAAALLAD
     TKVGVNAIVV GADRVAANGD TANKIGTYAL AVLAKYHGVK FLVAAPRTTI DMATASGKDI
     VIEQRAASEV TSIKGPRAGS EATDQIAIET VKIAAPGINV WNPAFDITPA SLIDGIITEV
     GVVEKGADEK YHLGGLFDGS TF
//

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