(data stored in ACNUC17492 zone)

HOGENOM: PIG4_94_PE2

ID   PIG4_94_PE2                          STANDARD;      PRT;   181 AA.
AC   PIG4_94_PE2; Q864Z2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 5; Short=RGS5;
DE   (PIG4_94.PE2).
GN   Name=RGS5;
OS   SUS SCROFA.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PIG4_94.PE2.
CC       Sus scrofa chromosome 4 Sscrofa9 partial sequence 90471001..91471000
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS5_PIG
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha,
CC       but not to G(s)-alpha (By similarity).
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Sus_scrofa;ENSSSCG00000006334;ENSSSCT00000006942;ENSSSCP00000006753.
DR   EMBL; AF139872; - ;
DR   EMBL; AJ549925; - ;
DR   UniProtKB/Swiss-Prot; Q864Z2; -.
DR   EMBL; AJ549925; CAD71257.1; -; mRNA.
DR   RefSeq; NP_999521.1; NM_214356.1.
DR   UniGene; Ssc.8330; -.
DR   ProteinModelPortal; Q864Z2; -.
DR   SMR; Q864Z2; 44-180.
DR   Ensembl; ENSSSCT00000006942; ENSSSCP00000006753; ENSSSCG00000006334.
DR   GeneID; 397640; -.
DR   KEGG; ssc:397640; -.
DR   CTD; 8490; -.
DR   OMA; HSCLERA; -.
DR   OrthoDB; EOG41RPW5; -.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 1.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; PIG4_94.PE2; -.
KW   ENSSSCG00000006334820036002503210000011;
KW   RGS5_PIG; Q9TU49_PIG; AF139872; AJ549925;
KW   Complete proteome; Signal transduction inhibitor.
SQ   SEQUENCE   181 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCKGLAALPH SCLERAKEIK IKLGILLQKP ESAVDLVIPY NEKPDKPVKI QKPSLDEALQ
     WRDSLDKLLQ NNYGLASFKS FLKSEFSEEN LEFWMACEDY KKIKSPVKMA EKAKKIYEEF
     IQSEAPKEVN IDHFTKEITM KNLVEPSPSS FDVAQKRIYA LMEKDSLPRF VRSEFYQEFI
     K
//

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