(data stored in SCRATCH3701 zone)

HOGENOM6: POLSJ_1_PE1764

ID   POLSJ_1_PE1764                       STANDARD;      PRT;   880 AA.
AC   POLSJ_1_PE1764; Q12CL1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (POLSJ_1.PE1764).
GN   OrderedLocusNames=Bpro_1795;
OS   POLAROMONAS SP. JS666.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=296591;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS POLSJ_1.PE1764.
CC       Polaromonas sp. JS666 chromosome, complete genome.
CC       7894705..8894704 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q12CL1_POLSJ
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q12CL1; -.
DR   EMBL; CP000316; ABE43731.1; -; Genomic_DNA.
DR   RefSeq; YP_548629.1; NC_007948.1.
DR   ProteinModelPortal; Q12CL1; -.
DR   SMR; Q12CL1; 30-533, 547-858.
DR   STRING; Q12CL1; -.
DR   GeneID; 4015542; -.
DR   GenomeReviews; CP000316_GR; Bpro_1795.
DR   KEGG; pol:Bpro_1795; -.
DR   NMPDR; fig|296591.1.peg.2811; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q12CL1; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; PSP296591:BPRO_1795-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; POLSJ_1.PE1764; -.
DR   PRODOM; POLSJ_1_PE1764.
DR   SWISS-2DPAGE; POLSJ_1_PE1764.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   880 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTQFAKETLP ISLEEEMRRS YLDYAMSVIV GRALPDARDG LKPVHRRVLF AMHELNNDWN
     RPYKKSARIV GDVIGKYHPH GDQSVYDTIV RMAQDFSLRH LLVDGQGNFG SVDGDNAAAM
     RYTEIRLSKI AHELLADLDK ETVDFGPNYD GSEQEPLVMP TRLPNLLVNG SGGIAVGMAT
     NIPPHNLNEV VDACLHMLKN PEASIDELME IVPAPDFPTG GIIYGINGVK DGYRTGRGKV
     VMRAKCHFED IDKGQRQSII VDELPYQVNK KTLQERMAEL VHEKKIEGIS HIQDESDKSG
     MRLVIELKRG EVPEVVLNNL YKQTQLQDTF GINMVALVNG QPKLCNLKDL IQVFLSHRRE
     VVTRRTVFTL RKARERGHVL EGLAVALANI DDFIAIIRNA PTPPVAKAEL MLRPWDSSLV
     REMLTRTRAD GGVVNADDYR PDGLEKAFGM GSDGLYRLSE TQAQEILQMR LQRLTGLEQD
     KIVAEYKEVM AEIDDLLDIL AKPERVSIII GEELSAIKLE FGQTKLGARR SQIEHSSFDL
     STEDLITPTD MVVTLSHSGY IKSQPLSEYR AQKRGGRGKQ ATATKEDDWV DQLFIANTHD
     YILCFSNRGR LYWLKVWEVP AGSRGSRGRP IVNMFPLQEG EKITVVLPLT GEKRSFPADQ
     YVFMATSMGT VKKTTLDEFS NPRKAGIIAV DLDDGDYLIG ASLTDGKHDV MLFSDGGKAV
     RFDENDVRPM GRNARGVRGM TLEDGQGVIA MLVAEDEQQS VLTATQNGYG KRTSITEYTR
     HGRGTKGMIA IQQSERNGKV VAATLVHVDD EIMLITDKGV LVRTRVSEIR EMGRATQGVT
     LIGLDEGSQL SGLQRIVEND ATLDDNDVEN DAGKDASTPL
//

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