(data stored in ACNUC7421 zone)

HOGENOM: POLSQ_1_PE1013

ID   POLSQ_1_PE1013                       STANDARD;      PRT;   397 AA.
AC   POLSQ_1_PE1013; A4SXM1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Carbamoyl-phosphate synthase small chain; EC=6.3.5
DE   5;AltName: Full=Carbamoyl-phosphate synthetase glutamine chain;
DE   (POLSQ_1.PE1013).
GN   Name=carA; OrderedLocusNames=Pnuc_1019;
OS   POLYNUCLEOBACTER NECESSARIUS SUBSP. ASYMBIOTICUS QLW-P1DMWA-1.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Polynucleobacter.
OX   NCBI_TaxID=312153;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS POLSQ_1.PE1013.
CC       Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1, complete
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:CARA_POLSQ
CC   -!- CATALYTIC ACTIVITY: 2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2
CC       ADP + phosphate + L-glutamate + carbamoyl phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis;
CC       carbamoyl phosphate from bicarbonate: step 1/1.
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC       pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
CC   -!- SUBUNIT: Composed of two chains; the small (or glutamine) chain
CC       promotes the hydrolysis of glutamine to ammonia, which is used by
CC       the large (or ammonia) chain to synthesize carbamoyl phosphate (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the CarA family.
CC   -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain.
CC   -!- GENE_FAMILY: HOG000038087 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A4SXM1; -.
DR   EMBL; CP000655; ABP34235.1; -; Genomic_DNA.
DR   RefSeq; YP_001155799.1; NC_009379.1.
DR   ProteinModelPortal; A4SXM1; -.
DR   SMR; A4SXM1; 11-394.
DR   STRING; A4SXM1; -.
DR   GeneID; 5053547; -.
DR   GenomeReviews; CP000655_GR; Pnuc_1019.
DR   KEGG; pnu:Pnuc_1019; -.
DR   eggNOG; COG0505; -.
DR   OMA; FTYPELG; -.
DR   PhylomeDB; A4SXM1; -.
DR   ProtClustDB; CLSK2323798; -.
DR   BioCyc; PSP312153:PNUC_1019-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01209; CPSase_S_chain; 1; -.
DR   InterPro; IPR001317; CarbamoylP_synth_GATase_dom.
DR   InterPro; IPR006274; CarbamoylP_synth_ssu.
DR   InterPro; IPR002474; CarbamoylP_synth_ssu_N.
DR   InterPro; IPR011702; GATASE.
DR   InterPro; IPR017926; GATASE_1.
DR   Gene3D; G3DSA:3.50.30.20; G3DSA:3.50.30.20; 1.
DR   Pfam; PF00988; CPSase_sm_chain; 1.
DR   Pfam; PF00117; GATase; 1.
DR   PRINTS; PR00099; CPSGATASE.
DR   PRINTS; PR00096; GATASE.
DR   SUPFAM; SSF52021; CP_synthsmall; 1.
DR   TIGRFAMs; TIGR01368; CPSaseIIsmall; 1.
DR   PROSITE; PS51273; GATASE_TYPE_1; 1.
DR   HOGENOMDNA; POLSQ_1.PE1013; -.
KW   carbamoyl-phosphate synthase, small subunit;
KW   Amino-acid biosynthesis; Arginine biosynthesis; ATP-binding;
KW   Complete proteome; Glutamine amidotransferase; Ligase;
KW   Nucleotide-binding; Pyrimidine biosynthesis.
SQ   SEQUENCE   397 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSPLLPSFPF AVLALADGSI FHGFSIGAPG ETTGEVVFNT ALTGYQEIIT DPSYCSQIVT
     LTYPHIGNVG VNAQDAESDR IHAAGLVIKD LPKRVSNFRS EAPLDAYLTE AGVVGIAGID
     TRKLTRILRD KGAQSGAIVA GKAGDDYETL GKKALELVKA FPGMAGLDLA KVVTTKKPYE
     WREGEWDLHG PNGTPAYRTL DTSKPTYKVV AYDFGVKRNI LRMLTERGCE LTVVPAQTSA
     AEVLAMQPDG VFLSNGPGDP EPCDYAIAAA KEIIEAGVPT FGICLGHQIM GLAAGAKTLK
     MKFGHHGANH PVKDLDTGRV AITSQNHGFA VDASTLPANV RVTHVSLFDG SLQGLAWKDK
     PAICFQGHPE ASPGPHDVSY LFDRFMELMN AAKKEGK
//

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