(data stored in ACNUC21562 zone)

HOGENOM: PONPY11_53_PE4

ID   PONPY11_53_PE4                       STANDARD;      PRT;   330 AA.
AC   PONPY11_53_PE4; Q4QXU3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Mas-related G-protein coupled receptor member X2;
DE   (PONPY11_53.PE4).
GN   Name=MRGPRX2; Synonyms=MRGX2;
OS   PONGO PYGMAEUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Hominoidea; Hominidae; Ponginae; Pongo.
OX   NCBI_TaxID=9600;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PONPY11_53.PE4.
CC       Pongo pygmaeus chromosome 11 PPYG2 partial sequence 50399610..51329248
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:MRGX2_PONPY
CC   -!- FUNCTION: Orphan receptor. Probably involved in the function of
CC       nociceptive neurons. May regulate nociceptor function and/or
CC       development, including the sensation or modulation of pain (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Mas subfamily.
CC   -!- GENE_FAMILY: HOG000015412 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Pongo_pygmaeus;ENSPPYG00000003427;ENSPPYT00000004082;ENSPPYP00000003934.
DR   EMBL; AY651165; - ;
DR   UniProtKB/Swiss-Prot; Q4QXU3; -.
DR   EMBL; AY651165; AAW70078.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q4QXU3; -.
DR   GeneTree; ENSGT00550000074531; -.
DR   InParanoid; Q4QXU3; -.
DR   OrthoDB; EOG4MW86R; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR000276; 7TM_GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_supfam.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   HOGENOMDNA; PONPY11_53.PE4; -.
KW   ENSPPYG00000003427820036002503210000011;
KW   MRGX2_PONPY; AY651165;
KW   Cell membrane; G-protein coupled receptor; Membrane; Receptor;
KW   Transducer; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   330 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDPTTPAWGN ESTTMNGNDQ ALPLLCGKET LIPVFLILFI ALVGLVGNGF VLWLLGFCMR
     RNAFSVYVLS LAGADFLFLC FQLINCLVYL SNFFCSISID FPSFFTTVMT CAYLAGLSML
     STISTERCLS VLWPIWYRCR RPRHLSAVVC VLLWALSLLL SILEGKFCGF FFSDGDSGWC
     QTFDFITAAW LIFLFMVLCG SSLALLVRIL CGSRGLPLTR LYLTILLTVL VFLLCGLPFG
     IQWFLILWIW ENSDVLFCHI HPVSVVLSSL NSSANPIIYF FVGTFRKQWR LQQPILKLAL
     QRALQDTAEV DHSEGCFRQG TPEMSRSSLV
//

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