(data stored in SCRATCH zone)

HOGENOM: PROM1_1_PE1001

ID   PROM1_1_PE1001                       STANDARD;      PRT;   1182 AA.
AC   PROM1_1_PE1001; A2C254;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Putative methionine synthase; EC=2.1.1 13;
DE   (PROM1_1.PE1001).
GN   Name=metH; OrderedLocusNames=NATL1_10061;
OS   PROCHLOROCOCCUS MARINUS STR. NATL1A.
OC   Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167555;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PROM1_1.PE1001.
CC       Prochlorococcus marinus str. NATL1A, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:A2C254_PROM1
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- GENE_FAMILY: HOG000251408 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A2C254; -.
DR   EMBL; CP000553; ABM75564.1; -; Genomic_DNA.
DR   RefSeq; YP_001014829.1; NC_008819.1.
DR   ProteinModelPortal; A2C254; -.
DR   STRING; A2C254; -.
DR   GeneID; 4779773; -.
DR   GenomeReviews; CP000553_GR; NATL1_10061.
DR   KEGG; pme:NATL1_10061; -.
DR   eggNOG; COG1410; -.
DR   OMA; ADCIAMS; -.
DR   ProtClustDB; CLSK893539; -.
DR   BioCyc; PMAR167555:NATL1_10061-MONOMER; -.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR   GO; GO:0008898; F:homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008705; F:methionine synthase activity; IEA:EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR011005; Dihydropteroate_synth-like.
DR   InterPro; IPR003759; Met_synth_Cbl-bd.
DR   InterPro; IPR011822; MetH.
DR   InterPro; IPR000489; Pterin-binding.
DR   InterPro; IPR003726; S_MeTrfase.
DR   InterPro; IPR004223; VitB12-dep_Met_synth_activ_dom.
DR   Gene3D; G3DSA:3.40.50.280; B12_bd; 1.
DR   Gene3D; G3DSA:3.20.20.20; Dhdropt_synth; 1.
DR   Gene3D; G3DSA:3.10.196.10; Met_synth_B12; 1.
DR   Gene3D; G3DSA:1.10.1240.10; Met_synth_B12_bd; 1.
DR   Gene3D; G3DSA:3.20.20.330; S_methyl_trans; 1.
DR   Pfam; PF02310; B12-binding; 1.
DR   Pfam; PF02607; B12-binding_2; 1.
DR   Pfam; PF02965; Met_synt_B12; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   Pfam; PF02574; S-methyl_trans; 1.
DR   PIRSF; PIRSF000381; MetH; 1.
DR   SUPFAM; SSF52242; Cbl-bd; 1.
DR   SUPFAM; SSF51717; DHP_synth_like; 1.
DR   SUPFAM; SSF56507; Met_synth_B12; 1.
DR   SUPFAM; SSF47644; Met_synth_Cbl-bd; 1.
DR   SUPFAM; SSF82282; S_methyl_trans; 1.
DR   TIGRFAMs; TIGR02082; MetH; 1.
DR   PROSITE; PS50974; ADOMET_ACTIVATION; 1.
DR   PROSITE; PS51332; B12_BINDING; 1.
DR   PROSITE; PS51337; B12_BINDING_NTER; 1.
DR   PROSITE; PS50970; HCY; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
DR   HOGENOMDNA; PROM1_1.PE1001; -.
KW   Cobalamin; Cobalt; Complete proteome; Metal-binding;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase; Zinc.
SQ   SEQUENCE   1182 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTHFLDYLNS EKRPIIVFDG ATGTSLQDQQ LTADDYGGAS LEGCNENLVL SSVSSVEKVH
     QSFLEAGCDV IETNTFGATS IVLDEYGIGN KAYEINFKAA QIARRIANKY QTPEKPRFVA
     GSIGPTTKLP TLGHISFDEL KKSYLEQAKA LIEGGIDLFL IETCQDVLQI KAALQSVNEA
     IGDGIKIPVM VSVTMETTGQ MLIGSDISSI TTILEPFSID ILGLNCATGP EEMKDHIKYL
     SEHSPFHISC IPNAGLPENV GGKAHYRLTP MELKFQLSHF INDLGVQLIG GCCGTRPEHI
     KQLSDLSLEL LSSDRRLINL SKKRSIIPAA SSIYESIPYE QDNSFLIVGE RLNASGSKKV
     RELLNIEDWD GLVGIAKSQL KENAHVLDVN VDFVGRNGIE DMSNLVKRLV NNINLPLMLD
     STDYEKMESG LKRAGGKCIL NSTNYEDGQD RFHKVIDLAK EHGSAVVIGT IDEDGMARAA
     EKKAEIATRA FKDATNSGLK PYEIFYDPLA LPISTGLEED RKNGFETIKA IKLIKDRHPQ
     VHLILGISNV SFGLSSSARV VLNSIFLNEA IKAGLDSAIV SPSKILPLNK ISEEEIKICL
     DLIYDKRIID NSVCTYDPLT TLTSYFDDSK KTLNNSSIDE DINLPIEDKL KNHIIDGEKT
     NLHSNLNLAL NKYKPLIIIN EYLLDGMKVV GELFGSGQMQ LPFVLQSAET MKYAVSYLED
     FMDKSEVNQS KGKFIIATVK GDVHDIGKNL VDIILSNNGY DVINLGIKQD VNAIIKAQKE
     HHADCIAMSG LLVKSTAFMK DNLKALNEED IDVPIILGGA ALTPKFVNQD CASVYKGKVI
     YGRDAFTDLK FMDAYMKAKL ANNWNNKTGF SEGAPEGITI GTYKSSNSDP KVIKESLEVK
     KVNDNSRSKD ISSVKSIKPP FLGPKVLLEK DIDLSNVYKF LDRNALFAGQ WQMKRSKDMS
     ASDYKEFLKQ KAEPKLDYWM NKIINDNLIS PSLVYGYFPC GREGNYLNVY DTDHKSLLGK
     FLLPRQRSGK RYCIADFYND LVDNHPSDYL PMQAVTMGEK ASDYSHKLFS QDSYSDYLYF
     HGLTVQLAEA LAEYIHSIIR IECGFKYEEP DNIKDILDVK YRGCRYSFGY PACPEVSDSR
     KQLDWLDADK INISMDESEQ LHPEQSTTAI VALHPVAKYF GI
//

If you have problems or comments...

PBIL Back to PBIL home page