(data stored in ACNUC7421 zone)

HOGENOM: PROM5_1_PE1014

ID   PROM5_1_PE1014                       STANDARD;      PRT;   276 AA.
AC   PROM5_1_PE1014; A2BWR2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase A; EC=2.1.1
DE   182;AltName: Full=16S rRNA (PROM5_1.PE1014)
DE   (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase;AltName:
DE   Full=16S rRNA dimethyladenosine transferase;AltName: Full=16S rRNA
DE   dimethylase;AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA)
DE   dimethyltransferase; .
GN   Name=rsmA; Synonyms=ksgA; OrderedLocusNames=P9515_10161;
OS   PROCHLOROCOCCUS MARINUS STR. MIT 9515.
OC   Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167542;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PROM5_1.PE1014.
CC       Prochlorococcus marinus str. MIT 9515, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:RSMA_PROM5
CC   -!- FUNCTION: Specifically dimethylates two adjacent adenosines (A1518
CC       and A1519) in the loop of a conserved hairpin near the 3'-end of
CC       16S rRNA in the 30S particle. May play a critical role in
CC       biogenesis of 30S subunits (By similarity).
CC   -!- CATALYTIC ACTIVITY: 4 S-adenosyl-L-methionine +
CC       adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-
CC       homocysteine + N(6)-dimethyladenine(1518)/N(6)-
CC       dimethyladenine(1519) in 16S rRNA.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. rRNA
CC       adenine N(6)-methyltransferase family. RsmA subfamily.
CC   -!- GENE_FAMILY: HOG000227962 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A2BWR2; -.
DR   EMBL; CP000552; ABM72223.1; -; Genomic_DNA.
DR   RefSeq; YP_001011330.1; NC_008817.1.
DR   ProteinModelPortal; A2BWR2; -.
DR   STRING; A2BWR2; -.
DR   GeneID; 4719164; -.
DR   GenomeReviews; CP000552_GR; P9515_10161.
DR   KEGG; pmc:P9515_10161; -.
DR   eggNOG; COG0030; -.
DR   OMA; LPHPAKD; -.
DR   ProtClustDB; PRK00274; -.
DR   BioCyc; PMAR167542:P9515ORF_1064-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   HAMAP; MF_00607; 16SrRNA_methyltr_A; 1; -.
DR   InterPro; IPR023165; rRNA_Ade_diMease-like.
DR   InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR   InterPro; IPR001737; rRNA_Ade_methylase_transferase.
DR   InterPro; IPR020598; rRNA_Ade_methylase_Trfase_N.
DR   InterPro; IPR011530; rRNA_adenine_dimethylase.
DR   Gene3D; G3DSA:1.10.8.100; rRNA_Ade_diMease-like; 1.
DR   PANTHER; PTHR11727; RRNA_meth_trans; 1.
DR   Pfam; PF00398; RrnaAD; 1.
DR   SMART; SM00650; rADc; 1.
DR   TIGRFAMs; TIGR00755; KsgA; 1.
DR   PROSITE; PS01131; RRNA_A_DIMETH; 1.
DR   HOGENOMDNA; PROM5_1.PE1014; -.
KW   dimethyladenosine transferase;
KW   Complete proteome; Cytoplasm; Methyltransferase; RNA-binding;
KW   rRNA processing; S-adenosyl-L-methionine; Transferase.
SQ   SEQUENCE   276 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNFKNHHQKK RFGQHWLVNN LILEKIKEVA ELDEKDFILE IGPGKGALTS KLLDSKISRL
     HAVELDKDLI DLLNNKFRND KKFSLQQGDI LSTNLDSINK KITKVIANIP YNITGPILDI
     FIGRLGIVSK NNYKKIIFLM QKDVVDRILS KESSKNAGAM SVRMQLISNI KRICDVPPSS
     FNPPPKVFSS LVVFEPLRPE KRLDIKLERY IDKLLQISFN SRRKMIRNTL NSILSEDEIK
     KLAELSEICF NSRPQDISIN KWIKLAEGCI KITNKN
//

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