(data stored in SCRATCH3701 zone)

HOGENOM6: PROM5_1_PE1151

ID   PROM5_1_PE1151                       STANDARD;      PRT;   863 AA.
AC   PROM5_1_PE1151; A2BX49;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase/topoisomerase IV, subunit A; EC=5.99.1 3;
DE   (PROM5_1.PE1151).
GN   OrderedLocusNames=P9515_11531;
OS   PROCHLOROCOCCUS MARINUS STR. MIT 9515.
OC   Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167542;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PROM5_1.PE1151.
CC       Prochlorococcus marinus str. MIT 9515, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:A2BX49_PROM5
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A2BX49; -.
DR   EMBL; CP000552; ABM72360.1; -; Genomic_DNA.
DR   RefSeq; YP_001011467.1; NC_008817.1.
DR   ProteinModelPortal; A2BX49; -.
DR   STRING; A2BX49; -.
DR   GeneID; 4719046; -.
DR   GenomeReviews; CP000552_GR; P9515_11531.
DR   KEGG; pmc:P9515_11531; -.
DR   eggNOG; COG0188; -.
DR   OMA; QRENVIV; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; PMAR167542:P9515ORF_1204-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; PROM5_1.PE1151; -.
DR   PRODOM; PROM5_1_PE1151.
DR   SWISS-2DPAGE; PROM5_1_PE1151.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   863 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDIVDSGDS SLSENNERII QTDLRNEMSR SYLEYAMSVI VGRALPDARD GLKPVHRRIL
     YAMYELGLTS GRPYRKCARV VGEVLGKYHP HGDTAVYDAL VRMAQDFSMR MPLIDGHGNF
     GSVDNDPPAA MRYTESRLQS LTDESLLEDI ESETVDFSDN FDGSQQEPTV LPARIPQLLL
     NGSSGIAVGM ATNIPPHNLG ELINGLKSII KNPLMEDKEL FELIKGPDFP TGGQILGRDG
     IKETFKSGRG SITMRGVADI EQIKSPGRAE KDAVIITELP FQTNKAALIE RIADLVNDKK
     LEGISDIRDE SDRDGMRIVI ELKRDAYPQV VLNNLFKLTP LQNNFSANIL ALVNGEPTTL
     SLRKMLDVFL DFRIVTIKRR TTFLLKKAEE RDHIIKGLLL ALEAMDNIIN LIRSAKDTTS
     AREQLQKDHE LSVIQADAIL QMQLRRLTAL EADKIKSEHD ELTRKITDYK NILQDKDRIN
     EIILEELSKI DERFSSPRKT EILNLGGGLD DIDLIANERS VVLLTSAGYL KRMPVSEFES
     TSRGSRGKAG TKNQEDDEVN LFISCNDHDT LLLFSDRGVA YALPAYRVPM SSRTAKGTPS
     VQLLPIPREE QITSIVSVES FDNDRYLLML TKAGFIKRTP LSAFSKIRSN GLIAINLEEG
     DALTWVRLSK EGDSVLIGSS KGMTIHFRLD NNELRPLGRT ARGVKSMNLK DGDKLVSMDV
     LTSDLVDQLA SLENENDEDI ESNSSKGPWV LVASAFGLGK RVPVAQFRLQ KRAGMGLRAI
     KFRIKDDSLV GLKVLGEGEE LIFVTERGVI VRTNADKISQ QSRAATGVRL QRLDDGDHLS
     EVVLVPHEQI DDSDQLMTKE EEL
//

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