(data stored in ACNUC7421 zone)

HOGENOM: PROMH_1_PE1007

ID   PROMH_1_PE1007                       STANDARD;      PRT;   326 AA.
AC   PROMH_1_PE1007; B4ETL6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose
DE   transferase; EC=2.7.8 30;AltName: Full=Undecaprenyl-phosphate Ara4FN
DE   transferase; Short=Ara4FN transferase; (PROMH_1.PE1007).
GN   Name=arnC; OrderedLocusNames=PMI1044;
OS   PROTEUS MIRABILIS HI4320.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Proteus.
OX   NCBI_TaxID=529507;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PROMH_1.PE1007.
CC       Proteus mirabilis HI4320 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:ARNC_PROMH
CC   -!- FUNCTION: Catalyzes the transfer of 4-deoxy-4-formamido-L-
CC       arabinose from UDP to undecaprenyl phosphate. The modified
CC       arabinose is attached to lipid A and is required for resistance to
CC       polymyxin and cationic antimicrobial peptides (By similarity).
CC   -!- CATALYTIC ACTIVITY: UDP-4-deoxy-4-formamido-beta-L-arabinose + di-
CC       trans,octa-cis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-
CC       alpha-L-arabinose di-trans,octa-cis-undecaprenyl phosphate.
CC   -!- PATHWAY: Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-
CC       arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-
CC       alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-
CC       formamido-beta-L-arabinose and undecaprenyl phosphate: step 1/2.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC   -!- GENE_FAMILY: HOG000283251 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B4ETL6; -.
DR   EMBL; AM942759; CAR42270.1; -; Genomic_DNA.
DR   RefSeq; YP_002150794.1; NC_010554.1.
DR   ProteinModelPortal; B4ETL6; -.
DR   STRING; B4ETL6; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   GeneID; 6799908; -.
DR   GenomeReviews; AM942759_GR; PMI1044.
DR   OMA; FIIGAEV; -.
DR   ProtClustDB; PRK10714; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   HAMAP; MF_01164; ArnC_transfer; 1; -.
DR   InterPro; IPR022857; ArnC_tfrase.
DR   InterPro; IPR001173; Glyco_trans_2.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   HOGENOMDNA; PROMH_1.PE1007; -.
KW   Antibiotic resistance; Cell inner membrane; Cell membrane;
KW   Complete proteome; Glycosyltransferase; Lipid A biosynthesis;
KW   Lipid synthesis; Lipopolysaccharide biosynthesis; Membrane;
KW   Transferase; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   326 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSTFEKINKV SVVIPVYNEE ESLPQLLERT IKSCKQLEQE YELILVDDGS SDNSAKMLEE
     AANIEDNHVI AIILNRNYGQ HSAIMAGFNQ ADGDLVITLD ADLQNPPEEI PRLVATAEEG
     YDVVGTRRRN RQDSWFRKTA SKMINAMITK ATGRSMGDYG CMLRAYRRHI IDAMLQCHER
     STFIPILANT FARRTIEIEV AHAEREYGDS KYSFLKLINL MYDLLTCLTT APLRLLSVVG
     SVIAVAGFLL AVLLIVLRLI FGAIWAADGV FTLFAILFMF IGAQFVAMGL LGEYIGRIYN
     DVRARPRYFI QKVVGVKKPN KNQEED
//

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