(data stored in ACNUC7421 zone)

HOGENOM: PROMH_1_PE1010

ID   PROMH_1_PE1010                       STANDARD;      PRT;   553 AA.
AC   PROMH_1_PE1010; B4ETL9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose
DE   arabinosyl transferase 2; EC=2.4.2 43;AltName:
DE   Full=4-amino-4-deoxy-L-arabinose lipid A transferase 2;AltName:
DE   Full=Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase;AltName:
DE   Full=Undecaprenyl phosphate-alpha-L-Ara4N transferase 2;
DE   (PROMH_1.PE1010).
GN   Name=arnT2; OrderedLocusNames=PMI1047;
OS   PROTEUS MIRABILIS HI4320.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Proteus.
OX   NCBI_TaxID=529507;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PROMH_1.PE1010.
CC       Proteus mirabilis HI4320 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:ARNT2_PROMH
CC   -!- FUNCTION: Catalyzes the transfer of the L-Ara4N moiety of the
CC       glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The
CC       modified arabinose is attached to lipid A and is required for
CC       resistance to polymyxin and cationic antimicrobial peptides (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: 4-amino-4-deoxy-alpha-L-arabinose di-
CC       trans,poly-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A)
CC       + di-trans,poly-cis-undecaprenyl phosphate.
CC   -!- PATHWAY: Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-
CC       arabinose-lipid A biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 83 family.
CC   -!- GENE_FAMILY: HOG000273002 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B4ETL9; -.
DR   EMBL; AM942759; CAR42273.1; -; Genomic_DNA.
DR   RefSeq; YP_002150797.1; NC_010554.1.
DR   STRING; B4ETL9; -.
DR   CAZy; GT83; Glycosyltransferase Family 83.
DR   GeneID; 6802570; -.
DR   GenomeReviews; AM942759_GR; PMI1047.
DR   OMA; RFAMDDA; -.
DR   ProtClustDB; PRK13279; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000030; F:mannosyltransferase activity; IEA:InterPro.
DR   GO; GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:InterPro.
DR   GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IEA:InterPro.
DR   HAMAP; MF_01165; ArnT_transfer; 1; -.
DR   InterPro; IPR022839; ArnT_tfrase.
DR   InterPro; IPR003342; Glyco_trans_39.
DR   Pfam; PF02366; PMT; 1.
DR   HOGENOMDNA; PROMH_1.PE1010; -.
KW   Cell inner membrane; Cell membrane; Complete proteome;
KW   Glycosyltransferase; Lipid A biosynthesis; Lipid synthesis;
KW   Lipopolysaccharide biosynthesis; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   553 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLNNRASKIG AILLALFFVL TYLFPLNSRL LWQPDETRYA EISREMVVSG NWIVPHMLDI
     RYFEKPIAGY WINNISQLIF GHTNFAVRFG SVISILLSAL LIYLLARMMW RNRQVAFVAS
     LIYLSMFLVF SVGTYSVLDP MLALWVTASM VCCFWALKAT TAKTRILAWI TLGLACGMAF
     MTKGFLALAI PVIVMIPVTL YQKQFTRMLL YGVLAVLSAA LISLPWVLAV AKAEPDYWHY
     FFWVEHIQRF SGDDAQHSSP FWYYIPIILL GVIPWLGLLP GALTSAWKKR RKRPELFFLL
     CWFVVPFLFF SIAKGKLPTY MLPFMGPLAM LMAKYGVDCA RKFKMKALRI NGYINIFIGV
     AAVVAILIIQ LVSSKPIYMP YEWSKWVLAI VAFSLWGIIG YLCSTLNGKH WLWAASCSLG
     VSLCIGQAIP NSSIDGKLPQ EFIRQNIDTL NASKYIVSNS VGVGAGLAWE LQRSDIYLYE
     RTGELTYGIE YPDSQHRLLK PESFEQWLEN ARKEGNVSVV ITYKDPKKLA QMPRPEELVT
     NRRMAILTYE KRK
//

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