(data stored in SCRATCH3701 zone)

HOGENOM6: PROMH_1_PE1676

ID   PROMH_1_PE1676                       STANDARD;      PRT;   877 AA.
AC   PROMH_1_PE1676; B4EZ29;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (PROMH_1.PE1676).
GN   Name=gyrA; OrderedLocusNames=PMI1732;
OS   PROTEUS MIRABILIS HI4320.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Proteus.
OX   NCBI_TaxID=529507;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PROMH_1.PE1676.
CC       Proteus mirabilis HI4320 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:B4EZ29_PROMH
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B4EZ29; -.
DR   EMBL; AM942759; CAR43604.1; -; Genomic_DNA.
DR   RefSeq; YP_002151463.1; NC_010554.1.
DR   STRING; B4EZ29; -.
DR   GeneID; 6802846; -.
DR   GenomeReviews; AM942759_GR; PMI1732.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; PROMH_1.PE1676; -.
DR   PRODOM; PROMH_1_PE1676.
DR   SWISS-2DPAGE; PROMH_1_PE1676.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   877 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDIAREITP VNIEEELKSS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMNVLGNDWN
     KPYKKSARVV GDVIGKYHPH GDSAVYETIV RLAQPFSMRY MLVDGQGNFG SVDGDSAAAM
     RYTEVRMAKI AHELLADLEK ETVDFVPNYD GTENIPAVMP TRIPNLLVNG SSGIAVGMAT
     NIPPHNLGEV IDGCLAYVDN EDITIEELME YITGPDFPTA AIINGRRGIL DAYRTGRGKI
     YIRAQADIET DEKTGRETII VTEIPYQVNK ARLIEKIAEL VKDKRIEGIS GLRDESDKDG
     MRIVVEIKRD AVGEVVLNHL FSQTQMQVSF GINMVALHQG QPKLLNLKEI IAAFIRHRRE
     VVTRRTIFEL RKARDRAHIL EALAVALANI DPVIELIRQA PTPAEAKAAL IAQPWDLGSV
     SAMLERAGDS NVARPEWLEP QFGVHDGKYY LTEQQAQAIL DLRLQKLTGL EHEKLLDEYR
     ELLLQIAELL HILRSPERLM DVIREELTAI KTQYNDPRRT EITENTADIN IEDLINEENV
     VVTLSHQGYV KYQPLTDYEA QRRGGKGKSA ARIKEEDFID RLLVANTHDT ILCFSSRGRL
     YWMKVYQLPE ASRGARGRPI INLLPLEQDE RITAILPVRE YEEGKFVFMA TASGTVKKTP
     LQDFSRPRSA GIIAVNLNDG DELIGVDLTD GSNEAMLFSA DGKVVRFAEE CVRPMGRTAT
     GVRGMKLVDD DKVVSLIIPR GEGDILTVTE NGYGKRTVQS EYPTKNRATQ GVISIKVSER
     NGKVVGAIQV EETDQIMMIT NAGTLVRTRV SEVSIVGRNT QGVTLIRTTE DELVVGLQRV
     EDEDDALDDD EVDEMISDNI SDVPESEPTD DADSEEE
//

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