(data stored in SCRATCH zone)

HOGENOM: PROMP_1_PE1003

ID   PROMP_1_PE1003                       STANDARD;      PRT;   390 AA.
AC   PROMP_1_PE1003; Q7V179;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Phosphoribosylglycinamide formyltransferase 2; Short=GART
DE   2; EC=2.1.2 -;AltName: Full=5'-phosphoribosylglycinamide transformylase
DE   2;AltName: Full=Formate-dependent GAR transformylase;AltName: Full=GAR
DE   transformylase 2; (PROMP_1.PE1003).
GN   Name=purT; OrderedLocusNames=PMM1004;
OS   PROCHLOROCOCCUS MARINUS SUBSP. PASTORIS STR. CCMP1986.
OC   Bacteria; Cyanobacteria; Prochlorales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=59919;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PROMP_1.PE1003.
CC       Prochlorococcus marinus subsp. pastoris str. CCMP1986, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:PURT_PROMP
CC   -!- FUNCTION: Catalyzes two reactions: the first one is the production
CC       of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP
CC       and beta GAR; the second, a side reaction, is the production of
CC       acetyl phosphate and ADP from acetate and ATP (By similarity).
CC   -!- CATALYTIC ACTIVITY: Formate + ATP + 5'-phospho-ribosylglycinamide
CC       = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate.
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-
CC       phospho-D-ribosyl)glycinamide (formate route): step 1/1.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the purK/purT family.
CC   -!- SIMILARITY: Contains 1 ATP-grasp domain.
CC   -!- GENE_FAMILY: HOG000072820 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q7V179; -.
DR   EMBL; BX548174; CAE19463.1; -; Genomic_DNA.
DR   RefSeq; NP_893121.1; NC_005072.1.
DR   HSSP; P33221; 1KJ8.
DR   ProteinModelPortal; Q7V179; -.
DR   STRING; Q7V179; -.
DR   GeneID; 1725841; -.
DR   GenomeReviews; BX548174_GR; PMM1004.
DR   KEGG; pmm:PMM1004; -.
DR   NMPDR; fig|59919.1.peg.1000; -.
DR   eggNOG; COG0027; -.
DR   OMA; TMNRKAI; -.
DR   ProtClustDB; PRK09288; -.
DR   BioCyc; PMAR167540:PMM1004-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_01643; PurT; 1; -.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR003135; ATP-grasp_carboxylate-amine.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR013816; ATP_grasp_subdomain_2.
DR   InterPro; IPR013817; Pre-ATP_grasp.
DR   InterPro; IPR016185; PreATP-grasp-like.
DR   InterPro; IPR005862; PurT.
DR   InterPro; IPR011054; Rudment_hybrid_motif.
DR   Gene3D; G3DSA:3.30.1490.20; ATP_grasp_subdomain_1; 1.
DR   Gene3D; G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
DR   Gene3D; G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
DR   PANTHER; PTHR23047:SF2; PurT; 1.
DR   Pfam; PF02222; ATP-grasp; 1.
DR   SUPFAM; SSF52440; PreATP-grasp-like; 1.
DR   SUPFAM; SSF51246; Rudmnt_hyb_motif; 1.
DR   TIGRFAMs; TIGR01142; PurT; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   HOGENOMDNA; PROMP_1.PE1003; -.
KW   phosphoribosylglycinamide formyltransferase 2;
KW   ATP-binding; Complete proteome; Magnesium; Metal-binding;
KW   Nucleotide-binding; Purine biosynthesis; Transferase.
SQ   SEQUENCE   390 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSSFKFIPKK ILLLGSGELG KELVVEAKRL GLEVIAIDKY ENAPAMQLAD NSFVIDMSDK
     EILKKKIKEL NPDFVVPEIE ALSIEALKEL EDEGINIVPN ARTVEITMNR DKIRDLASKE
     LNIKTAKFSY VFNVDELEIK SSEIGFPLLI KPLMSSSGKG QSLVNRKEDL LLAWNDALKN
     SRGKIVGVIL EEFLNFDYEF TLLTIRKTSG ENIFCEPIGH EQYKGDYQCS WQPLDMNQSL
     INEARKMTTK ILNNLNGSGI YGVEFFVRGK EVIFSELSPR PHDTGMVTLV SQNINEFELH
     LRAFLNLPIP NISLLKPSAT RVIISDKESN TPSYSGLNEA LELENTKVLI FGKPTAKKGR
     RMGVVLSTDD DLNIARENAD KSALKIKIVS
//

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