(data stored in SCRATCH9089 zone)

HOGENOM6: PSAER1_1_PE4964

ID   PSAER1_1_PE4964                      STANDARD;      PRT;   754 AA.
AC   PSAER1_1_PE4964; Q9HUK1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase 4 subunit A; EC=5.99.1 -;AltName:
DE   Full=Topoisomerase IV subunit A; (PSAER1_1.PE4964).
GN   Name=parC; OrderedLocusNames=PA4964;
OS   PSEUDOMONAS AERUGINOSA PAO1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PSAER1_1.PE4964.
CC       Pseudomonas aeruginosa PAO1 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:PARC_PSEAE
CC   -!- FUNCTION: Topoisomerase IV is essential for chromosome
CC       segregation. It relaxes supercoiled DNA. Performs the decatenation
CC       events required during the replication of a circular DNA molecule
CC       (By similarity).
CC   -!- SUBUNIT: Composed of two subunits: ParC and ParE (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein
CC       (By similarity).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076277 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q9HUK1; -.
DR   EMBL; AE004091; AAG08349.1; -; Genomic_DNA.
DR   PIR; G83025; G83025.
DR   RefSeq; NP_253651.1; NC_002516.2.
DR   ProteinModelPortal; Q9HUK1; -.
DR   SMR; Q9HUK1; 35-749.
DR   PhosSite; Q9HUK1; -.
DR   GeneID; 879741; -.
DR   GenomeReviews; AE004091_GR; PA4964.
DR   KEGG; pae:PA4964; -.
DR   PseudoCAP; PA4964; -.
DR   OMA; ILAITNE; -.
DR   ProtClustDB; PRK05561; -.
DR   BioCyc; PAER208964:PA4964-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   InterPro; IPR005742; TopoIV_A_Gneg.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 2.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01062; ParC_Gneg; 1.
DR   HOGENOMDNA; PSAER1_1.PE4964; -.
DR   PRODOM; PSAER1_1_PE4964.
DR   SWISS-2DPAGE; PSAER1_1_PE4964.
KW   DNA topoisomerase IV subunit A;
KW   Cell membrane; Complete proteome; DNA-binding; Isomerase; Membrane;
KW   Reference proteome; Topoisomerase.
SQ   SEQUENCE   754 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSESLDLSLE GVERRSLAEF TEQAYLNYSM YVIMDRALPH IGDGLKPVQR RIVYAMSELG
     LDADSKHKKS ARTVGDVLGK FHPHGDSACY EAMVLMAQPF SYRYPLVDGQ GNWGAPDDPK
     SFAAMRYTEA RLSRYSEVLL SELGQGTVDW VPNFDGTLDE PAVLPARLPN LLLNGTTGIA
     VGMATDVPPH NLREVASACV RLLDQPGATV AELCEHVPGP DFPTEAEIIT PRADLQKVYE
     TGRGSVRMRA VYRVEDGDIV IHALPHQVSG SKVLEQIAGQ MQAKKLPMVA DLRDESDHEN
     PTRIVIIPRS NRVDVEELMT HLFATTDLET SYRVNLNIIG LDGKPQVKDL RQLLSEWLQF
     RIGTVRRRLQ FRLDKVERRL HLLDGLLIAF LNLDEVIHII RTEDQPKAVL MERFELSEVQ
     ADYILDTRLR QLARLEEMKI RGEQEELLKE QKRLQTLLGS EAKLKKLVRE ELIKDAETYG
     DDRRSPIVAR AEARALSETE LMPTEPVTVV LSEKGWVRCA KGHDIDAAGL SYKAGDGFKA
     AAPGRSNQYA VFIDSTGRSY SLPAHSLPSA RGQGEPLSGR LTPPPGASFE CVLLPDDDAL
     FVIASDAGYG FVVKGEDLQA KNKAGKALLS LPNGSAVVAP RPVRDVEQDW LAAVTTEGRL
     LLFKVSDLPQ LGKGKGNKII GIPGERVASR EEYLTDLAVL PAGATLVLQA GKRTLSLKGD
     DLEHYKGERG RRGNKLPRGF QRVDSLLVDI PPQD
//

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