(data stored in ACNUC7421 zone)

HOGENOM: PSEA6_1_PE1015

ID   PSEA6_1_PE1015                       STANDARD;      PRT;   509 AA.
AC   PSEA6_1_PE1015; Q15X40;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Histidine ammonia-lyase; Short=Histidase; EC=4.3.1 3;
DE   (PSEA6_1.PE1015).
GN   Name=hutH; OrderedLocusNames=Patl_1022;
OS   PSEUDOALTEROMONAS ATLANTICA T6C.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=342610;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PSEA6_1.PE1015.
CC       Pseudoalteromonas atlantica T6c, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:HUTH_PSEA6
CC   -!- CATALYTIC ACTIVITY: L-histidine = urocanate + NH(3).
CC   -!- PATHWAY: Amino-acid degradation; L-histidine degradation into L-
CC       glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- PTM: Contains an active site 4-methylidene-imidazol-5-one (MIO),
CC       which is formed autocatalytically by cyclization and dehydration
CC       of residues Ala-Ser-Gly (By similarity).
CC   -!- SIMILARITY: Belongs to the PAL/histidase family.
CC   -!- GENE_FAMILY: HOG000237619 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q15X40; -.
DR   EMBL; CP000388; ABG39548.1; -; Genomic_DNA.
DR   RefSeq; YP_660602.1; NC_008228.1.
DR   ProteinModelPortal; Q15X40; -.
DR   SMR; Q15X40; 7-502.
DR   STRING; Q15X40; -.
DR   GeneID; 4173301; -.
DR   GenomeReviews; CP000388_GR; Patl_1022.
DR   KEGG; pat:Patl_1022; -.
DR   NMPDR; fig|342610.3.peg.3978; -.
DR   eggNOG; COG2986; -.
DR   OMA; QKGQIDS; -.
DR   ProtClustDB; PRK09367; -.
DR   BioCyc; PATL342610:PATL_1022-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004397; F:histidine ammonia-lyase activity; IEA:EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006548; P:histidine catabolic process; IEA:InterPro.
DR   HAMAP; MF_00229; His_ammonia-lyase; 1; -.
DR   InterPro; IPR005921; HutH.
DR   InterPro; IPR008948; L-Aspartase-like.
DR   InterPro; IPR024083; L-Aspartase-like_N.
DR   InterPro; IPR001106; Phe/His_NH3-lyase.
DR   InterPro; IPR022313; Phe/His_NH3-lyase_AS.
DR   Gene3D; G3DSA:1.10.275.10; G3DSA:1.10.275.10; 1.
DR   Pfam; PF00221; PAL; 1.
DR   SUPFAM; SSF48557; L-Aspartase-like; 1.
DR   TIGRFAMs; TIGR01225; HutH; 1.
DR   PROSITE; PS00488; PAL_HISTIDASE; 1.
DR   HOGENOMDNA; PSEA6_1.PE1015; -.
KW   histidine ammonia-lyase;
KW   Complete proteome; Cytoplasm; Histidine metabolism; Lyase.
SQ   SEQUENCE   509 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEQKYLLQPG KLTIETMRQV HRRHVPITLA PDSFERIHSA EQTVRDVITQ GRTVYGINTG
     FGLLANTKIE VDELELLQRS IVLSHAAGIG TLMSASTVRL LMLLKINSLA RGYSGIRLIV
     IEALIALYNH QVYPAIPEKG SVGASGDLAP LAHMSAVLLG EGEVIYQGNQ ISAEKGLMIA
     GLQPISLAPK EGLALLNGTQ ASTAFALQGL FYAENALTSS IAIGALSVDA ALGSRVPFNE
     RIHIVRGHQA QIDVATGFRT LLQESEIGKS HGGCEKVQDP YSLRCQPQVM GACLQQMRFA
     KQILVTEANG VSDNPIVFSE SDDVLSGGNF HAETVAMAAD MLAIALAEIG ALSERRMALL
     IDSSLSGLPP FLVDNGGVNS GFMIAQVTSA ALASENKSYA HPASIDSLPT SANQEDHVSM
     ATFAGRRLRD IFDNVAGILA IEWLAASQGI DFRFPLKTST QLQSVHALMR SKVTFYDKDR
     YFSPDIEQAK LLITRHSLSD LVQQDIQLL
//

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