(data stored in SCRATCH3701 zone)

HOGENOM6: PSEF5_1_PE4255

ID   PSEF5_1_PE4255                       STANDARD;      PRT;   889 AA.
AC   PSEF5_1_PE4255; Q4K8M7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (PSEF5_1.PE4255).
GN   Name=gyrA; OrderedLocusNames=PFL_4314;
OS   PSEUDOMONAS FLUORESCENS PF-5.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=220664;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PSEF5_1.PE4255.
CC       Pseudomonas fluorescens Pf-5, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q4K8M7_PSEF5
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q4K8M7; -.
DR   EMBL; CP000076; AAY93569.1; -; Genomic_DNA.
DR   RefSeq; YP_261406.1; NC_004129.6.
DR   ProteinModelPortal; Q4K8M7; -.
DR   SMR; Q4K8M7; 30-522, 537-842.
DR   STRING; Q4K8M7; -.
DR   GeneID; 3478437; -.
DR   GenomeReviews; CP000076_GR; PFL_4314.
DR   KEGG; pfl:PFL_4314; -.
DR   NMPDR; fig|220664.3.peg.6126; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q4K8M7; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; PFLU220664:PFL_4314-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; PSEF5_1.PE4255; -.
DR   PRODOM; PSEF5_1_PE4255.
DR   SWISS-2DPAGE; PSEF5_1_PE4255.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   889 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGELAKEILP VNIEDELKQS YLDYAMSVIV GRALPDARDG LKPVHRRVLY AMSELGNDWN
     KPYKKSARVV GDVIGKYHPH GDTAVYDTIV RMAQPFSLRY LLVDGQGNFG SVDGDNAAAM
     RYTEVRMTKL AHELLADLHK ETVDWVPNYD GTEMIPAVMP TKIPNLLVNG SSGIAVGMAT
     NIPPHNLGEV IDGCLALIDN PELTVDELMQ YIPGPDFPTA AIINGREGII EAYRTGRGRI
     YMRARSIIED IDKVGGRQQI VITELPYQLN KARLIEKIAE LVKEKKLEGI TELRDESDKD
     GMRVVIELRR GEVPEVILNN LYAQTQLQAV FGINIVALID GRPRILNLKD LLEAFVRHRR
     EVVTRRTVFE LRKARERGHI LEGQAVALSN IDPVIALIKA SPTPSEAKEA LISTPWESSA
     VMTMVERAGA DSCRPENLDP QYGLRDGKYF LSPEQAQAIL ELRLHRLTGL EHEKLLAEYQ
     EILNQIGELI RILNSATRLM EVIREELEVI RAEYGDVRRT EILDARLDLT LGDMIPEEER
     VVTISHGGYA KTQPLAAYQA QRRGGKGKSA TGVKDEDYIA HLLVANSHTT LLLFSSKGKV
     YWLKTYEIPE ASRAARGRPL VNLLPLDEGE YITTMLPVEE YTEGHYIFMA TANGTVKKTP
     LESFSRQRSV GLIALELDEG DVLISAAITD GEREVMLFSD GGKVTRFKES DVRAMGRTAR
     GVRGMRLAEG QKLISMLIPE EGSQILTASE RGFGKRTAIG EFPEYKRGGQ GVIAMVSNER
     NGRLVGAVQV LDGEEIMLIS DQGTLVRTRV DEVSSLGRNT QGVTLIKLAS DETLVGLERV
     QEPSEIEGEE FEGEEGAEFE GAVLDAVADT DEAAEGQQAD AAGEEESQD
//

If you have problems or comments...

PBIL Back to PBIL home page