(data stored in ACNUC7421 zone)

HOGENOM: PSEMY_1_PE1002

ID   PSEMY_1_PE1002                       STANDARD;      PRT;   338 AA.
AC   PSEMY_1_PE1002; A4XR11;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ketol-acid reductoisomerase; EC=1.1.1 86;AltName:
DE   Full=Acetohydroxy-acid isomeroreductase;AltName:
DE   Full=Alpha-keto-beta-hydroxylacil reductoisomerase; (PSEMY_1.PE1002).
GN   Name=ilvC; OrderedLocusNames=Pmen_1009;
OS   PSEUDOMONAS MENDOCINA YMP.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=399739;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS PSEMY_1.PE1002.
CC       Pseudomonas mendocina ymp, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:ILVC_PSEMY
CC   -!- CATALYTIC ACTIVITY: (R)-2,3-dihydroxy-3-methylbutanoate + NADP(+)
CC       = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH.
CC   -!- CATALYTIC ACTIVITY: (2R,3R)-2,3-dihydroxy-3-methylpentanoate +
CC       NADP(+) = (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-isoleucine biosynthesis; L-
CC       isoleucine from 2-oxobutanoate: step 2/4.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-valine biosynthesis; L-valine
CC       from pyruvate: step 2/4.
CC   -!- SIMILARITY: Belongs to the ketol-acid reductoisomerase family.
CC   -!- GENE_FAMILY: HOG000016230 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A4XR11; -.
DR   EMBL; CP000680; ABP83777.1; -; Genomic_DNA.
DR   RefSeq; YP_001186509.1; NC_009439.1.
DR   ProteinModelPortal; A4XR11; -.
DR   SMR; A4XR11; 1-327.
DR   STRING; A4XR11; -.
DR   GeneID; 5108631; -.
DR   GenomeReviews; CP000680_GR; Pmen_1009.
DR   KEGG; pmy:Pmen_1009; -.
DR   eggNOG; COG0059; -.
DR   OMA; MAYAKGI; -.
DR   PhylomeDB; A4XR11; -.
DR   ProtClustDB; PRK05479; -.
DR   BioCyc; PMEN399739:PMEN_1009-MON; -.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0004455; F:ketol-acid reductoisomerase activity; IEA:EC.
DR   GO; GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00435; IlvC; 1; -.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR013023; AcH_isomrdctse.
DR   InterPro; IPR000506; AcH_isomrdctse_C.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR013116; IlvN.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   PANTHER; PTHR21371; AcH_isomrdctse; 1.
DR   Pfam; PF01450; IlvC; 1.
DR   Pfam; PF07991; IlvN; 1.
DR   SUPFAM; SSF48179; 6DGDH_C_like; 1.
DR   TIGRFAMs; TIGR00465; IlvC; 1.
DR   HOGENOMDNA; PSEMY_1.PE1002; -.
KW   ketol-acid reductoisomerase;
KW   Amino-acid biosynthesis; Branched-chain amino acid biosynthesis;
KW   Complete proteome; NADP; Oxidoreductase.
SQ   SEQUENCE   338 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKVYYDKDCD LSIIQGKKVA IIGYGSQGHA QACNLKDSGV DVTIGLRKGS ATVAKAEAHG
     LKVTDVASAV AAADLVMILT PDEFQGQLYK NEIEPNIKKG ATLAFSHGFA IHYNQVVPRA
     DLDVIMIAPK APGHTVRTEF VKGGGIPDLI AVYQDASGNA KNVALSYASG VGGGRTGIIE
     TTFKDETETD LFGEQAVLCG GTVELVKAGF ETLVEAGYAP EMAYFECLHE LKLIVDLMYE
     GGIANMNYSI SNNAEYGEYV TGPEVINAES RQAMRNALKR IQDGEYAKMF ISEGATGYPS
     MTAKRRNNAA HGIEVIGEQL RAMMPWIAAN KIVDKTKN
//

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