(data stored in ACNUC4266 zone)

HOVERGEN: Q0PD64_MOUSE

ID   Q0PD64_MOUSE            Unreviewed;       216 AA.
AC   Q0PD64;
DT   19-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   19-SEP-2006, sequence version 1.
DT   03-NOV-2009, entry version 26.
DE   SubName: Full=Rab2B;
DE   SubName: Full=RAB2B, member RAS oncogene family, isoform CRA_a;
GN   Name=Rab2b; Synonyms=Rab2B; ORFNames=mCG_122128;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Balb/c;
RX   PubMed=16923123; DOI=10.1111/j.1365-2443.2006.00997.x;
RA   Itoh T., Satoh M., Kanno E., Fukuda M.;
RT   "Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing
RT   proteins based on their Rab-binding activity.";
RL   Genes Cells 11:1023-1037(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Balb/c;
RX   MEDLINE=22590425; PubMed=12578829; DOI=10.1074/jbc.M212341200;
RA   Fukuda M.;
RT   "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2.
RT   Identification of a critical determinant of Rab3A/Rab27A recognition
RT   by Rim2.";
RL   J. Biol. Chem. 278:15373-15380(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Balb/c;
RX   MEDLINE=21922892; PubMed=11856727; DOI=10.1074/jbc.C200005200;
RA   Fukuda M., Kuroda T.S., Mikoshiba K.;
RT   "Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
RT   implications of a tripartite protein complex for melanosome
RT   transport.";
RL   J. Biol. Chem. 277:12432-12436(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Balb/c;
RX   MEDLINE=21883924; PubMed=11773082; DOI=10.1074/jbc.M112414200;
RA   Kuroda T.S., Fukuda M., Ariga H., Mikoshiba K.;
RT   "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2
RT   functions as a novel Rab27A binding domain.";
RL   J. Biol. Chem. 277:9212-9218(2002).
RN   [5]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mixed;
RX   MEDLINE=22036378; PubMed=12040188; DOI=10.1126/science.1069193;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R.,
RA   Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A.,
RA   Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.,
RA   Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K.,
RA   Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J.,
RA   Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R.,
RA   Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H.,
RA   Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A.,
RA   Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A.,
RA   Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C.,
RA   Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C.,
RA   Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B.,
RA   Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E.,
RA   Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R.,
RA   Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C.,
RA   Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L.,
RA   Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S.,
RA   Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L.,
RA   Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R.,
RA   Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R.,
RA   Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J.,
RA   Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L.,
RA   Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C.,
RA   Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A.,
RA   Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H.,
RA   Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L.,
RA   Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M.,
RA   Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K.,
RA   Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S.,
RA   Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J.,
RA   Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G.,
RA   Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.;
RT   "A comparison of whole-genome shotgun-derived mouse chromosome 16 and
RT   the human genome.";
RL   Science 296:1661-1671(2002).
RN   [6]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mixed;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
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CC   -!- GENE_FAMILY: HBG009351 [ FAMILY / ALN / TREE ]
DR   EMBL; AB232586; BAF02848.1; -; mRNA.
DR   EMBL; CH466659; EDL42248.1; -; Genomic_DNA.
DR   EMBL; CH466659; EDL42249.1; -; Genomic_DNA.
DR   IPI; IPI00187430; -.
DR   RefSeq; NP_766189.1; -.
DR   UniGene; Mm.32870; -.
DR   SMR; Q0PD64; 4-176.
DR   STRING; Q0PD64; -.
DR   PRIDE; Q0PD64; -.
DR   Ensembl; ENSMUST00000022765; ENSMUSP00000022765; ENSMUSG00000022159; Mus musculus.
DR   Ensembl; ENSMUST00000100631; ENSMUSP00000098197; ENSMUSG00000022159; Mus musculus.
DR   GeneID; 76338; -.
DR   KEGG; mmu:76338; -.
DR   CTD; 76338; -.
DR   MGI; MGI:1923588; Rab2b.
DR   HOVERGEN; Q0PD64; -.
DR   OMA; AKANANT; -.
DR   NextBio; 344953; -.
DR   ArrayExpress; Q0PD64; -.
DR   Bgee; Q0PD64; -.
DR   Genevestigator; Q0PD64; -.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR003579; GTPase_Rab.
DR   InterPro; IPR013753; Ras.
DR   InterPro; IPR001806; Ras_GTPase.
DR   InterPro; IPR005225; Small_GTP_bd.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00175; RAB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q0PD64.
DR   SWISS-2DPAGE; Q0PD64.
KW   GTP-binding; Nucleotide-binding.
SQ   SEQUENCE   216 AA;  24198 MW;  54EE7E2337BFD751 CRC64;
     MTYAYLFKYI IIGDTGVGKS CLLLQFTDKR FQPVHDLTIG VEFGARMVNI DGKQIKLQIW
     DTAGQESFRS ITRSYYRGAA GALLVYDITR RETFNHLTSW LEDARQHSSS NMVIMLIGNK
     SDLESRRDVK REEGEAFARE HGLIFMETSA KTACNVEEAY INTAKEIYRK IQQGLFDVHN
     EANGIKIGPQ QSITSSVGPC SPQQNVSDIG PDSGCC
//

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