(data stored in ACNUC3659 zone)

HOVERGEN: Q3SY19_HUMAN

ID   Q3SY19_HUMAN            Unreviewed;       247 AA.
AC   Q3SY19;
DT   11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT   11-OCT-2005, sequence version 1.
DT   03-NOV-2009, entry version 31.
DE   SubName: Full=PRSS1 protein;
GN   Name=PRSS1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=PCR rescued clones;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the peptidase S1 family.
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CC   -!- GENE_FAMILY: HBG013304 [ FAMILY / ALN / TREE ]
DR   EMBL; BC103998; AAI03999.1; -; mRNA.
DR   IPI; IPI00815665; -.
DR   UniGene; Hs.713534; -.
DR   SMR; Q3SY19; 24-247.
DR   STRING; Q3SY19; -.
DR   Ensembl; ENST00000290968; ENSP00000290968; ENSG00000204983; Homo sapiens.
DR   Ensembl; ENST00000311737; ENSP00000308720; ENSG00000204983; Homo sapiens.
DR   Ensembl; ENST00000311757; ENSP00000312576; ENSG00000204983; Homo sapiens.
DR   Ensembl; ENST00000361585; ENSP00000355222; ENSG00000204983; Homo sapiens.
DR   Ensembl; ENST00000438955; ENSP00000414534; ENSG00000204983; Homo sapiens.
DR   Ensembl; ENST00000486171; ENSP00000417854; ENSG00000204983; Homo sapiens.
DR   Ensembl; ENST00000492062; ENSP00000419912; ENSG00000204983; Homo sapiens.
DR   HGNC; HGNC:9475; PRSS1.
DR   HOVERGEN; Q3SY19; -.
DR   ArrayExpress; Q3SY19; -.
DR   Bgee; Q3SY19; -.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR018114; Peptidase_S1/S6_AS.
DR   InterPro; IPR001254; Peptidase_S1_S6.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR009003; Ser/Cys_Pept_Trypsin-like.
DR   Pfam; PF00089; Trypsin; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q3SY19.
DR   SWISS-2DPAGE; Q3SY19.
KW   Hydrolase; Protease; Serine protease.
SQ   SEQUENCE   247 AA;  26556 MW;  F717A5F4528BCCBD CRC64;
     MNPLLILTFV AAALAAPFDD DDKIVGGYNC EENSVPYQVS LNSGYHFCGG SLINEQWVVS
     AGHCYKSRIQ VRLGEHNIEV LEGNEQFINA AKIIRHPQYD RKTLDNDILL IKLSSPAVIN
     SRVSAISLPT APPAAGTESL ISGWGNTLSS GADYPDELQC LDAPVLSQAE CEASYPGKIT
     NNMFCVGFLE GGKDSCQGDS GGPVVSNGEL QGIVSWGYGC AQKNRPGVYT KVYNYVDWIK
     DTIAANS
//

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