(data stored in ACNUC4932 zone)

HOVERGEN: Q6LDV5_RAT

ID   Q6LDV5_RAT              Unreviewed;       304 AA.
AC   Q6LDV5;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   03-NOV-2009, entry version 30.
DE   SubName: Full=Rat 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase;
DE   Flags: Fragment;
GN   Name=Pfkfb1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=87184586; PubMed=3032183; DOI=10.1016/0006-291X(87)90364-0;
RA   Colosa A.D., Lively M.O., El-Maghrabi M.R., Pilkis S.J.;
RT   "Isolation of a cDNA clone for rat liver 6-phosphofructo 2-
RT   kinase/fructose 2,6-bisphosphatase.";
RL   Biochem. Biophys. Res. Commun. 143:1092-1098(1987).
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CC   -!- GENE_FAMILY: HBG005628 [ FAMILY / ALN / TREE ]
DR   EMBL; M15685; AAA40624.1; -; mRNA.
DR   IPI; IPI00327110; -.
DR   UniGene; Rn.10115; -.
DR   HSSP; P16118; 1K6M.
DR   SMR; Q6LDV5; 1-304.
DR   STRING; Q6LDV5; -.
DR   Ensembl; ENSRNOT00000000178; ENSRNOP00000000178; ENSRNOG00000000165; Rattus norvegicus.
DR   Ensembl; ENSRNOT00000033656; ENSRNOP00000035212; ENSRNOG00000000165; Rattus norvegicus.
DR   Ensembl; ENSRNOT00000065163; ENSRNOP00000059966; ENSRNOG00000000165; Rattus norvegicus.
DR   UCSC; X15579; rat.
DR   HOVERGEN; Q6LDV5; -.
DR   ArrayExpress; Q6LDV5; -.
DR   Genevestigator; Q6LDV5; -.
DR   GO; GO:0043540; C:6-phosphofructo-2-kinase/fructose-2,6-bipho...; IDA:RGD.
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IDA:RGD.
DR   GO; GO:0005524; F:ATP binding; IDA:RGD.
DR   GO; GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase act...; IDA:RGD.
DR   GO; GO:0070095; F:fructose-6-phosphate binding; IDA:RGD.
DR   GO; GO:0042802; F:identical protein binding; IDA:RGD.
DR   GO; GO:0019900; F:kinase binding; IPI:RGD.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:RGD.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; TAS:RGD.
DR   GO; GO:0031100; P:organ regeneration; IEP:RGD.
DR   GO; GO:0033133; P:positive regulation of glucokinase activity; IMP:RGD.
DR   GO; GO:0051591; P:response to cAMP; IEP:RGD.
DR   GO; GO:0033762; P:response to glucagon stimulus; IEP:RGD.
DR   GO; GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.
DR   GO; GO:0032868; P:response to insulin stimulus; IEP:RGD.
DR   GO; GO:0042594; P:response to starvation; IEP:RGD.
DR   InterPro; IPR003094; 6Pfruct_kin.
DR   InterPro; IPR013079; 6Phosfructo_kin.
DR   InterPro; IPR016260; Bifunct_6PFK/fruc_bisP_Ptase.
DR   InterPro; IPR001345; PG/BPGM_mutase_AS.
DR   InterPro; IPR013078; PG_mutase.
DR   PANTHER; PTHR10606; 6Pfruct_kin; 1.
DR   Pfam; PF01591; 6PF2K; 1.
DR   Pfam; PF00300; PGAM; 1.
DR   PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR   PRINTS; PR00991; 6PFRUCTKNASE.
DR   SMART; SM00855; PGAM; 1.
DR   PROSITE; PS00175; PG_MUTASE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q6LDV5.
DR   SWISS-2DPAGE; Q6LDV5.
KW   Kinase.
FT   NON_TER       1      1
SQ   SEQUENCE   304 AA;  35404 MW;  5D64BBEF657DF00F CRC64;
     AENIKQVKLG SPDYIDCDQE KVLEDFLKRI ECYEINYQPL DEELDSHLSY IKIFDVGTRY
     MVNRVQDHVQ SRTAYYLMNI HVTPRSIYLC RHGESELNLR GRIGGDSGLS ARGKQYAYAL
     ANFIRSQGIS SLKVWTSHMK RTIQTAEALG VPYEQWKALN EIDAGVCEEM TYEEIQEHYP
     EEFALRDQDK YRYRYPKGES YEDLVQRLEP VIMELERQEN VLVICHQAVM RCLLAYFLDK
     SSDELPYLKC PLHTVLKLTP VAYGCRVESI YLNVEAVNTH RDKPENVDIT REAEEALDTV
     PAHY
//

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