(data stored in ACNUC3659 zone)

HOVERGEN: Q7Z5F4_HUMAN

ID   Q7Z5F4_HUMAN            Unreviewed;       261 AA.
AC   Q7Z5F4;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   03-NOV-2009, entry version 38.
DE   SubName: Full=Protease serine 4 isoform B;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Guo J.H., Yu L.;
RT   "Molecular cloning and characterization of PRSS4B.";
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family.
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CC   -!- GENE_FAMILY: HBG013304 [ FAMILY / ALN / TREE ]
DR   EMBL; AY052783; AAL14243.1; -; mRNA.
DR   IPI; IPI00385250; -.
DR   UniGene; Hs.654513; -.
DR   HSSP; P35030; 1H4W.
DR   SMR; Q7Z5F4; 38-261.
DR   STRING; Q7Z5F4; -.
DR   PRIDE; Q7Z5F4; -.
DR   Ensembl; ENST00000342836; ENSP00000340889; ENSG00000010438; Homo sapiens.
DR   Ensembl; ENST00000361005; ENSP00000354280; ENSG00000010438; Homo sapiens.
DR   Ensembl; ENST00000379405; ENSP00000368715; ENSG00000010438; Homo sapiens.
DR   Ensembl; ENST00000429677; ENSP00000401828; ENSG00000010438; Homo sapiens.
DR   Ensembl; ENST00000457896; ENSP00000401249; ENSG00000010438; Homo sapiens.
DR   HGNC; HGNC:9486; PRSS3.
DR   HOVERGEN; Q7Z5F4; -.
DR   ArrayExpress; Q7Z5F4; -.
DR   Bgee; Q7Z5F4; -.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR018114; Peptidase_S1/S6_AS.
DR   InterPro; IPR001254; Peptidase_S1_S6.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR009003; Ser/Cys_Pept_Trypsin-like.
DR   Pfam; PF00089; Trypsin; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q7Z5F4.
DR   SWISS-2DPAGE; Q7Z5F4.
KW   Hydrolase; Protease; Serine protease.
FT   DOMAIN       26     77       PRODOM:2005.1:PD474467  1445
FT   DOMAIN       83    126       PRODOM:2005.1:PD331626  438
FT   DOMAIN      127    161       PRODOM:2005.1:PD701657  461
FT   DOMAIN      169    201       PRODOM:2005.1:PD251054  232
FT   DOMAIN      213    255       PRODOM:2005.1:PD000068  1525
SQ   SEQUENCE   261 AA;  28199 MW;  6B182C3BB9E7A5B3 CRC64;
     MHMRETSGFT LKKGRSAPLV FHPPDALIAV PFDDDDKIVG GYTCEENSLP YQVSLNSGSH
     FCGGSLISEQ WVVSAAHCYK SRIQVRLGEH NIKVLEGNEQ FINAAKIIRH PKYNRDTLDN
     DIMLIKLSSP AVINARVSTI SLPTAPPAAG TECLISGWGN TLSSGADYPD ELKCLDAPVL
     TQAECKASYP GKITNSMFCV GFLEGGKDSC QGDSGGPVVC NGQLQGVVSW GHGCAWKNRP
     GVYTKVYNYV DWIKDTIAAN S
//

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