(data stored in ACNUC4932 zone)

HOVERGEN: Q7ZU78_DANRE

ID   Q7ZU78_DANRE            Unreviewed;       522 AA.
AC   Q7ZU78;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   03-NOV-2009, entry version 38.
DE   SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2;
GN   Name=pfkfb2;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Whole body;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
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CC   -!- GENE_FAMILY: HBG005628 [ FAMILY / ALN / TREE ]
DR   EMBL; BC050514; AAH50514.1; -; mRNA.
DR   IPI; IPI00506341; -.
DR   RefSeq; NP_957302.1; -.
DR   UniGene; Dr.24973; -.
DR   HSSP; P07953; 1C80.
DR   Ensembl; ENSDART00000102328; ENSDARP00000093104; ENSDARG00000023840; Danio rerio.
DR   GeneID; 393983; -.
DR   KEGG; dre:393983; -.
DR   CTD; 393983; -.
DR   ZFIN; ZDB-GENE-040426-966; pfkfb2.
DR   HOVERGEN; Q7ZU78; -.
DR   Bgee; Q7ZU78; -.
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   InterPro; IPR003094; 6Pfruct_kin.
DR   InterPro; IPR013079; 6Phosfructo_kin.
DR   InterPro; IPR016260; Bifunct_6PFK/fruc_bisP_Ptase.
DR   InterPro; IPR001345; PG/BPGM_mutase_AS.
DR   InterPro; IPR013078; PG_mutase.
DR   PANTHER; PTHR10606; 6Pfruct_kin; 1.
DR   Pfam; PF01591; 6PF2K; 1.
DR   Pfam; PF00300; PGAM; 1.
DR   PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR   PRINTS; PR00991; 6PFRUCTKNASE.
DR   SMART; SM00855; PGAM; 1.
DR   PROSITE; PS00175; PG_MUTASE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q7ZU78.
DR   SWISS-2DPAGE; Q7ZU78.
KW   Kinase.
FT   DOMAIN       35    227       PRODOM:2005.1:PD324818  79
FT   DOMAIN      248    440       PRODOM:2005.1:PD858890  96
FT   DOMAIN      441    522       PRODOM:2005.1:PD752501  1
SQ   SEQUENCE   522 AA;  60124 MW;  A60B47D0FC90D7BB CRC64;
     MDSSNEHKKT EPRVTEKKCS WASHMTNSPT VIVLVGLPAR GKTYISKKLT RYLNWIGVPT
     KVFNLGVYRR EAVQSYKSYD FFRHDNEEAM KIRRQCAIVA LQDVKSYLNE EGGQIAVFDA
     TNTTRERRDL ILSFAQDHSY KVFFVESLCS DPEVIAANIM DVKVSSPDYP ERDRESVMED
     FLKRIECYKV TYQPLDPGEH DKALSFIQVI NVGQRFLVNR VQDYIQSKIV YYLMNIHVQK
     HSIYLCRHGE SQHNVQGCIG GDSELSSRGK EFSKALRGFL ETQKIPDLKV WTSQLRRTIQ
     TAEELGVPYE QWKILNEIDA GICEEMSYEK IKEAYPDEYS LRDQDKYHYR YPGGESYQDL
     VQRLEPVIME LERQGNVLVI CHQAVMRCLL AYFLDKSAND LPYLKCPLHA VLKLTPVAYG
     CKVDMFDLKV EAVNTHRDRP LGRGRQVVAP ALLRRNSFTP LSSQDQVKRP RLFSVGNPPR
     ITSAPALSTT RFPETRESEE LSESQELLNC FSPSDSKEVI QE
//

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