(data stored in ACNUC13530 zone)

HOVERGEN: Q8NHX0_HUMAN

ID   Q8NHX0_HUMAN            Unreviewed;       335 AA.
AC   Q8NHX0;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   03-NOV-2009, entry version 56.
DE   SubName: Full=Extracellular signal-related kinase 1c;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Aebersold D.M., Yung Y., Seger R.;
RT   "Properties of human ERK1c.";
RL   Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
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CC   -!- GENE_FAMILY: HBG014652 [ FAMILY / ALN / TREE ]
DR   EMBL; AY033608; AAK52330.1; -; mRNA.
DR   IPI; IPI00304111; -.
DR   UniGene; Hs.861; -.
DR   HSSP; P28482; 1PME.
DR   SMR; Q8NHX0; 29-330.
DR   STRING; Q8NHX0; -.
DR   PRIDE; Q8NHX0; -.
DR   Ensembl; ENST00000263025; ENSP00000263025; ENSG00000102882; Homo sapiens.
DR   Ensembl; ENST00000322266; ENSP00000327293; ENSG00000102882; Homo sapiens.
DR   Ensembl; ENST00000395199; ENSP00000378625; ENSG00000102882; Homo sapiens.
DR   Ensembl; ENST00000395200; ENSP00000378626; ENSG00000102882; Homo sapiens.
DR   Ensembl; ENST00000395202; ENSP00000378628; ENSG00000102882; Homo sapiens.
DR   Ensembl; ENST00000403394; ENSP00000384895; ENSG00000102882; Homo sapiens.
DR   HGNC; HGNC:6877; MAPK3.
DR   HOVERGEN; Q8NHX0; -.
DR   ArrayExpress; Q8NHX0; -.
DR   Bgee; Q8NHX0; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; IEA:InterPro.
DR   GO; GO:0006468; P:protein amino acid phosphorylation; IEA:InterPro.
DR   InterPro; IPR008349; Erk_1_2_MAPK.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR003527; MAP_kinase_CS.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR017442; Se/Thr_prot_kinase-like_dom.
DR   InterPro; IPR002290; Ser/Thr_prot_kinase_dom.
DR   Pfam; PF00069; Pkinase; 1.
DR   PRINTS; PR01770; ERK1ERK2MAPK.
DR   ProDom; PD000001; Prot_kinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   PROSITE; PS01351; MAPK; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q8NHX0.
DR   SWISS-2DPAGE; Q8NHX0.
KW   ATP-binding; Kinase; Nucleotide-binding.
FT   DOMAIN       48    247       PRODOM:2005.1:PD000001  8496
FT   DOMAIN      291    327       PRODOM:2005.1:PD054205  105
SQ   SEQUENCE   335 AA;  38249 MW;  A82027A684BA12E1 CRC64;
     MAAAAAQGGG GGEPRRTEGV GPGVPGEVEM VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY
     DHVRKTRVAI KKISPFEHQT YCQRTLREIQ ILLRFRHENV IGIRDILRAS TLEAMRDVYI
     VQDLMETDLY KLLKSQQLSN DHICYFLYQI LRGLKYIHSA NVLHRDLKPS NLLSNTTCDL
     KICDFGLARI ADPEHDHTGF LTEYVATRWY RAPEIMLNSK GYTKSIDIWS VGCILAEMLS
     NRPIFPGKHY LDQLNHILAL DLLDRMLTFN PNKRITVEEA LAHPYLEQYY DPTDEPVAEE
     PFTFAMELDD LPKERLKELI FQETARFQPG VLEAP
//

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