(data stored in ACNUC4266 zone)

HOVERGEN: RAB10_DISOM

ID   RAB10_DISOM             Reviewed;         200 AA.
AC   P22127;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   13-OCT-2009, entry version 55.
DE   RecName: Full=Ras-related protein Rab-10;
DE            Short=ORA1;
OS   Discopyge ommata (Electric ray).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Squalea; Hypnosqualea; Pristiorajea; Batoidea;
OC   Torpediniformes; Narcinoidei; Narcinidae; Discopyge.
OX   NCBI_TaxID=7785;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Electric lobe;
RX   MEDLINE=91115900; PubMed=1899244;
RA   Ngsee J.K., Elferink L.A., Scheller R.H.;
RT   "A family of ras-like GTP-binding proteins expressed in electromotor
RT   neurons.";
RL   J. Biol. Chem. 266:2675-2680(1991).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic
CC       side (Potential).
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
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CC   -!- GENE_FAMILY: HBG009351 [ FAMILY / ALN / TREE ]
DR   EMBL; M38390; AAA49230.1; -; mRNA.
DR   PIR; A38625; A38625.
DR   HSSP; P07560; 1G16.
DR   HOVERGEN; P22127; -.
DR   GO; GO:0009898; C:internal side of plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR003579; GTPase_Rab.
DR   InterPro; IPR013753; Ras.
DR   InterPro; IPR001806; Ras_GTPase.
DR   InterPro; IPR005225; Small_GTP_bd.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00175; RAB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; P22127.
DR   SWISS-2DPAGE; P22127.
KW   Cell membrane; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding;
KW   Prenylation.
FT   DOMAIN        9    173       PRODOM:2005.1:PD000015  2217
FT   CHAIN         1    200       Ras-related protein Rab-10.
FT                                /FTId=PRO_0000121149.
FT   NP_BIND      16     23       GTP (By similarity).
FT   NP_BIND      64     68       GTP (By similarity).
FT   NP_BIND     122    125       GTP (By similarity).
FT   LIPID       198    198       S-geranylgeranyl cysteine (By
FT                                similarity).
FT   LIPID       199    199       S-geranylgeranyl cysteine (By
FT                                similarity).
SQ   SEQUENCE   200 AA;  22623 MW;  41D38E3D760519C5 CRC64;
     MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELHGKKIKL
     QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNAKSFENI SKWLRNIDEH ANEDVERMLL
     GNKCDMEDKR VVLKSKGEQI AREHAIRFFE TSAKANINIE KAFLTLAEDI LQKTPVKEPD
     RENVDISTTG GGTGLKKCCS
//

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