(data stored in ACNUC26462 zone)

HOGENOM: RABIT10_28_PE3

ID   RABIT10_28_PE3                       STANDARD;      PRT;   413 AA.
AC   RABIT10_28_PE3; Q9GM70;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Serine/threonine-protein kinase 17A; EC=2.7.11 1;AltName:
DE   Full=DAP kinase-related apoptosis-inducing protein kinase 1;
DE   Short=rDRAK1; (RABIT10_28.PE3).
GN   Name=STK17A; Synonyms=DRAK1;
OS   ORYCTOLAGUS CUNICULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RABIT10_28.PE3.
CC       Oryctolagus cuniculus chromosome 10 oryCun2 partial sequence
CC       25950518..26950517 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:ST17A_RABIT
CC   -!- FUNCTION: Acts as a positive regulator of apoptosis. Appears to
CC       play a role in osteoclast apoptosis.
CC   -!- CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- TISSUE SPECIFICITY: Highly expressed in bone marrow. Lower levels
CC       in brain, heart, lung, liver and kidney.
CC   -!- PTM: Autophosphorylated (By similarity).
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK
CC       Ser/Thr protein kinase family. DAP kinase subfamily.
CC   -!- SIMILARITY: Contains 1 protein kinase domain.
CC   -!- GENE_FAMILY: HOG000233016 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Oryctolagus_cuniculus;ENSOCUG00000015953;ENSOCUT00000015950;ENSOCUP00000013707.
DR   EMBL; AB042195; - ;
DR   UniProtKB/Swiss-Prot; Q9GM70; -.
DR   EMBL; AB042195; BAB16111.1; -; mRNA.
DR   RefSeq; NP_001075475.1; NM_001082006.1.
DR   UniGene; Ocu.2549; -.
DR   ProteinModelPortal; Q9GM70; -.
DR   STRING; Q9GM70; -.
DR   Ensembl; ENSOCUT00000015950; ENSOCUP00000013707; ENSOCUG00000015953.
DR   GeneID; 100008622; -.
DR   CTD; 9263; -.
DR   eggNOG; maNOG09685; -.
DR   GeneTree; ENSGT00600000084221; -.
DR   BRENDA; 2.7.11.1; 1749.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptosis; IEA:UniProtKB-KW.
DR   GO; GO:0006917; P:induction of apoptosis; IMP:UniProtKB.
DR   GO; GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR017442; Se/Thr_kinase-like_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR002290; Ser/Thr_kinase_dom.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   HOGENOMDNA; RABIT10_28.PE3; -.
KW   ENSOCUG00000015953820036002503210000011;
KW   ST17A_RABIT; AB042195;
KW   Apoptosis; ATP-binding; Kinase; Nucleotide-binding; Nucleus;
KW   Phosphoprotein; Serine/threonine-protein kinase; Transferase.
SQ   SEQUENCE   413 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MIPLEKPGSG GSPSAAASGS GPGGRGQSAA RRPPALRTRG LLTEIRAAIR TEPFQDCYSL
     SPGRELGRGK FAVVRKCIQK DSGKEFAAKF MRKRRKGQDC RMEIIHEIAV LELAQDNPWV
     INLHEVYETS SEMILVLEYA AGGEIFDQCV ADRDEAFNEK DVQRLMRQIL EGVHFLHTHD
     VVHLDLKPQN ILLTSESPLG DIKIVDFGLS RIVKNSEELR EIMGTPEYVA PEILSYDPIS
     MATDMWSIGV LTYVMLTGIS PFLGDNKQET FLNISQMNLS YSEEEFDTVS ESAVDFIKKL
     LVKKPEDRAT AEECLKHPWL TQSSIQDPVL RVKEALEEAN ALQKGDSVPE ISSATEKPGT
     EESIVTEELI VVTSYTLGQC RQSEKEKMEQ KAISKRFKFE EPLLQEIPGE FIY
//

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