(data stored in ACNUC17492 zone)

HOGENOM: RABIT13_31_PE3

ID   RABIT13_31_PE3                       STANDARD;      PRT;   205 AA.
AC   RABIT13_31_PE3; Q0R4E4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 4; Short=RGS4;
DE   (RABIT13_31.PE3).
GN   Name=RGS4;
OS   ORYCTOLAGUS CUNICULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RABIT13_31.PE3.
CC       Oryctolagus cuniculus chromosome 13 oryCun2 partial sequence
CC       29567410..30567409 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS4_RABIT
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form. Activity on G(z)-alpha is inhibited
CC       by phosphorylation of the G-protein. Activity on G(z)-alpha and
CC       G(i)-alpha-1 is inhibited by palmitoylation of the G-protein (By
CC       similarity).
CC   -!- PTM: Palmitoylated on Cys-2 and/or Cys-12 (By similarity).
CC   -!- PTM: Phosphorylated by cyclic GMP-dependent protein kinase (By
CC       similarity).
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Oryctolagus_cuniculus;ENSOCUG00000005204;ENSOCUT00000005202;ENSOCUP00000004507.
DR   EMBL; DQ120011; - ;
DR   UniProtKB/Swiss-Prot; Q0R4E4; -.
DR   EMBL; DQ120011; AAZ94718.1; -; mRNA.
DR   RefSeq; NP_001075683.1; NM_001082214.1.
DR   UniGene; Ocu.6140; -.
DR   ProteinModelPortal; Q0R4E4; -.
DR   SMR; Q0R4E4; 51-177.
DR   STRING; Q0R4E4; -.
DR   Ensembl; ENSOCUT00000005202; ENSOCUP00000004507; ENSOCUG00000005204.
DR   GeneID; 100009014; -.
DR   CTD; 5999; -.
DR   eggNOG; maNOG17159; -.
DR   GeneTree; ENSGT00600000084388; -.
DR   OMA; DCPSLVP; -.
DR   OrthoDB; EOG4PK297; -.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 1.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; RABIT13_31.PE3; -.
KW   ENSOCUG00000005204820036002503210000011;
KW   RGS4_RABIT; DQ120011;
KW   Lipoprotein; Palmitate; Phosphoprotein; Signal transduction inhibitor.
SQ   SEQUENCE   205 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHNSSHS KKDKVVVCQR VSQEEVKKWA
     ESLENLINHE CGLAAFKAFL KSEYSEENID FWISCEEYKK IKSPSKLSPK AKKIYNEFIS
     VQATKEVNLD SCTREETSRN MLEPTITCFD EAQKKIFNLM EKDSYRRFLK SRFYLDLANP
     SNCGSEKQKG AKSSVDCASL LPQCA
//

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