(data stored in ACNUC14238 zone)

HOGENOM: RAT10_PE1001

ID   RAT10_PE1001                         STANDARD;      PRT;   550 AA.
AC   RAT10_PE1001; Q9Z0W0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Glucagon-like peptide 2 receptor; Short=GLP-2 receptor;
DE   Short=GLP-2-R; Short=GLP-2R; (RAT10.PE1001).
GN   Name=Glp2r;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT10.PE1001.
CC       Rattus norvegicus chromosome 10 RGSC3.4  sequence 1..110718848
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:GLP2R_RAT
CC   -!- FUNCTION: This is a receptor for glucagon-like peptide 2. The
CC       activity of this receptor is mediated by G proteins which activate
CC       adenylyl cyclase.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 2 family.
CC   -!- GENE_FAMILY: HOG000008250 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000003683;ENSRNOT00000004946;ENSRNOP00000004946.
DR   EMBL; AF105368; - ;
DR   EMBL; AF338223; - ;
DR   UniProtKB/Swiss-Prot; Q9Z0W0; -.
DR   EMBL; AF105368; AAD16896.1; -; mRNA.
DR   IPI; IPI00208235; -.
DR   RefSeq; NP_068620.1; NM_021848.1.
DR   UniGene; Rn.163105; -.
DR   ProteinModelPortal; Q9Z0W0; -.
DR   STRING; Q9Z0W0; -.
DR   PRIDE; Q9Z0W0; -.
DR   Ensembl; ENSRNOT00000004946; ENSRNOP00000004946; ENSRNOG00000003683.
DR   GeneID; 60432; -.
DR   KEGG; rno:60432; -.
DR   CTD; 9340; -.
DR   RGD; 620270; Glp2r.
DR   eggNOG; roNOG13254; -.
DR   GeneTree; ENSGT00580000081498; -.
DR   InParanoid; Q9Z0W0; -.
DR   OrthoDB; EOG48GW3K; -.
DR   PhylomeDB; Q9Z0W0; -.
DR   NextBio; 612158; -.
DR   ArrayExpress; Q9Z0W0; -.
DR   Genevestigator; Q9Z0W0; -.
DR   GermOnline; ENSRNOG00000003683; Rattus norvegicus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004967; F:glucagon receptor activity; IDA:RGD.
DR   GO; GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IDA:RGD.
DR   GO; GO:0042592; P:homeostatic process; TAS:RGD.
DR   InterPro; IPR017981; GPCR_2-like.
DR   InterPro; IPR001879; GPCR_2_extracellular_dom.
DR   InterPro; IPR000832; GPCR_2_secretin-like.
DR   InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR   Pfam; PF00002; 7tm_2; 1.
DR   Pfam; PF02793; HRM; 1.
DR   PRINTS; PR00249; GPCRSECRETIN.
DR   PROSITE; PS00649; G_PROTEIN_RECEP_F2_1; 1.
DR   PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; FALSE_NEG.
DR   PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR   PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR   HOGENOMDNA; RAT10.PE1001; -.
KW   ENSRNOG00000003683820036002503210000011;
KW   Glp2r; GLP2R_RAT; Q924C8_RAT; AF105368; AF338223;
KW   Cell membrane; Complete proteome; Disulfide bond;
KW   G-protein coupled receptor; Glycoprotein; Membrane; Receptor;
KW   Reference proteome; Transducer; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   550 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRPQPSPAVP SRCREAPVPR VRAQPVGIPE AQGPVPLHSQ QMRLLWGPGR PFLALLLLVS
     IKQVTGSLLK ETTQKWANYK EKCLEDLHNR LSGIFCNGTF DRYVCWPHSY PGNVSVPCPS
     YLPWWNAESP GRAYRHCLAQ GTWQTRENTT DIWQDESECS ENHSFRQNVD HYALLYTLQL
     MYTVGYSVSL ISLFLALTLF LFLRKLHCTR NYIHMNLFAS FILKVLAVLV KDMVSHNSYS
     KRPDDESGWM SYLSETSVSC RSVQVLLHYF VGTNHLWLLV EGLYLHTLLE PTVFPERRLW
     PKYLVVGWAF PMLFVIPWGF ARAHLENTRC WATNGNLKIW WIIRGPMLLC VTVNFFIFLK
     ILKLLISKLK AHQMCFRDYK YRLAKSTLLL IPLLGVHEVL FTFFPDDQVQ GFSKRIRLFI
     QLTLSSVHGF LVALQYGFAN GEVKAELRKS WGRFLLARHW GCRTCVLGKN FRFLGKCSKK
     LSEGDGSETL QKLRFSTCSS HLASETLGDV GVQPHRGRGA WPRGSSLSES SEGDFTLANT
     MEEILEESEI
//

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