(data stored in ACNUC8465 zone)

HOGENOM: RAT10_PE2384

ID   RAT10_PE2384                         STANDARD;      PRT;   334 AA.
AC   RAT10_PE2384; Q925D6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Mitogen-activated protein kinase kinase 6;SubName:
DE   Full=Mitogen-activated protein kinase kinase 6, isoform CRA_a;SubName:
DE   Full=Uncharacterized protein; (RAT10.PE2384).
GN   Name=Map2k6; Synonyms=Mkk6; ORFNames=rCG_34806;
OS   RATTUS NORVEGICUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS RAT10.PE2384.
CC       Rattus norvegicus chromosome 10 RGSC3.4  sequence 1..110718848
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q925D6_RAT
CC   -!- GENE_FAMILY: HOG000234206 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Rattus_norvegicus;ENSRNOG00000004437;ENSRNOT00000006217;ENSRNOP00000006217.
DR   EMBL; AF369384; - ;
DR   EMBL; BC087004; - ;
DR   EMBL; CH473948; - ;
DR   UniProtKB/Swiss-Prot; Q925D6; -.
DR   EMBL; BC087004; AAH87004.1; -; mRNA.
DR   EMBL; AF369384; AAK53428.1; -; mRNA.
DR   EMBL; CH473948; EDM06489.1; -; Genomic_DNA.
DR   IPI; IPI00205537; -.
DR   RefSeq; NP_446155.1; NM_053703.3.
DR   UniGene; Rn.17256; -.
DR   HSSP; Q13153; 1F3M.
DR   ProteinModelPortal; Q925D6; -.
DR   STRING; Q925D6; -.
DR   PhosphoSite; Q925D6; -.
DR   Ensembl; ENSRNOT00000006217; ENSRNOP00000006217; ENSRNOG00000004437.
DR   GeneID; 114495; -.
DR   KEGG; rno:114495; -.
DR   NMPDR; fig|10116.3.peg.6353; -.
DR   UCSC; NM_053703; rat.
DR   CTD; 5608; -.
DR   RGD; 620666; Map2k6.
DR   eggNOG; roNOG06770; -.
DR   GeneTree; ENSGT00570000078767; -.
DR   InParanoid; Q925D6; -.
DR   OrthoDB; EOG4P2Q2M; -.
DR   PhylomeDB; Q925D6; -.
DR   NextBio; 618541; -.
DR   ArrayExpress; Q925D6; -.
DR   Genevestigator; Q925D6; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptosis; IEP:RGD.
DR   GO; GO:0043065; P:positive regulation of apoptosis; IMP:RGD.
DR   GO; GO:0042493; P:response to drug; IEP:RGD.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR017442; Se/Thr_kinase-like_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR002290; Ser/Thr_kinase_dom.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   HOGENOMDNA; RAT10.PE2384; -.
KW   ENSRNOG00000004437820036002503210000011;
KW   Map2k6; Q925D6_RAT; AF369384; BC087004; CH473948;
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Reference proteome.
SQ   SEQUENCE   334 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSQSKGKKRN PGLKIPREAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA DDLEPIVELG
     RGAYGVVEKM RHVPSGQIMA VKRIRATVNS QEQKRLLMDL DVSMRTVDCP FTVTFYGALF
     REGDVWICME LMDTSLDKFY KQVIDKGQTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV
     KPSNVLINTL GQVKMCDFGI SGYLVDSVAK TIDAGCKPYM APERINPELN QKGYSVKSDI
     WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSADFVDF TSQCLKKNSK
     ERPTYPELMQ HPFFTVHEAK AADVASFVKL ILGD
//

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